Neurons, Synapses, and Signaling Part 2 Flashcards
Gated channel
- causes a change in membrane potential to occur
-Opens or closes in response to stimuli
Voltage gated ion channel
Opens or closes in response to a shift in the volatage across the plasma membrane or the neuron
When gated K+ channels open, K+ diffuses out which makes the inside of the cell more___
negative
Hyperpolarization
an increase in magnitude of the membrane potential
opening other types of ion channels triggers Depolarization.
a reduction in the magnitude of the membrane potential
Graded potentials
changes in polarization where the magnitude of the change varies with the strength of the stimulus.
- Graded potentials decay with time and distance from the source
If a depolarization shifts the membrane potential sufficiently, it results in a massive change in membrane voltage called
action potential
Action potentials have a constant magnitude and transmit signals over
short and long distances
Action potentials occur whenever a depolarization increases the membrane potential to a particular valve called a
threshold
Action potentials are all or
none
First stage of action potentials
Resting stage- Most Na+ channels are closed, but not all, of the volatage-gated potassium (k+) channels are also closed
Second stage of action potentials
Depolarization-A stimulus opens some sodium channels. Na+ flows into the cell. If the stimulus is strong enough, more Na+ channels open increasing Na- diffusion even more. If the depolarization reaches the threshold, it triggers an action potential.
Third stage of action potential
Once the threshold is crossed, this positive-feedback cycle rapidly
brings the membrane potential close to E N a
▪ This is called the rising phase
Deplorization opens most sodium channels while the potassium channels remain closed. Na+ influx makes the inside the membrane positive with respect to the outside
The fourth stage of action potential: Falling stage
During the falling phase, voltage-gated Na+ Channels become inactivated;voltage-gated channels open,and flows out of the cell
Refractory Period
During this period after an action
potential, a second action potential cannot be
initiated
* The refractory period is a result of a temporary
inactivation of the channels