Neurons, neurotransmitters and neuromodulators (2C) Flashcards

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1
Q

What is the neural synapse?

A

The region that includes the axon terminals of the presynaptic neuron, the synaptic gaps and the dendrites of the post synaptic neuron.

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2
Q

What is the presynaptic neuron?

A

The neuron that releases neurochemicals into the neural synapse.

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3
Q

What are axon terminals (or axon buttons)?

A

The end of a neuron (presynaptic) that releases neurochemicals into the neural synapse.

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4
Q

What is the synaptic gap?

A

The space between the presynaptic neuron and the postsynaptic neuron.

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5
Q

What is the postsynaptic neuron?

A

The neuron that receives neurochemicals from the neural synapse.

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6
Q

What is the dendrite?

A

A branched extension of a neuron (post synaptic) on which receptor sites are located.

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7
Q

What is a receptor site in relation to neurons?

A

A protein molecule on the dendrites of a neuron that receives neurochemicals.

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8
Q

What is a neurochemical?

A

A chemical substance that transmits neural information within the nervous system.

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9
Q

What is synaptic transmission?

A

The chemical conveyance of neural information between two neurons across a neural synapse.

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10
Q

What is the first step in synaptic transmission?

A

Neurochemicals are produced in the axon terminals of the presynaptic neuron.

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11
Q

What is the second step in synaptic transmission?

Hint- it is after neurochemicals are produced.

A

Neurochemicals are released from the axon terminals into the synaptic gap.

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12
Q

What is the third step in synaptic transmission?

Hint- it is after neurochemicals are released into the synaptic gap.

A

Neurochemicals bind to receptor sites on the dendrites of the postsynaptic neuron.

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12
Q

What are neurotransmitters?

A

Chemical molecules that have an effect on one or two postsynaptic neurons. They enables rapid communication and are two types, either excitatory or inhibitory.

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12
Q

What is action potential?

A

An electrical impulse that travels down the axon of a neuron.

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12
Q

What is the fourth step in synaptic transmission?

Hint- it is after neurochemicals bind to receptor sites.

A

Neurochemicals affect the postsynaptic neuron, either triggering or inhibiting a response.

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13
Q

What is an excitatory affect?

A

When the neurotransmitter increases the likelihood of the postsynaptic neuron firing an action potential.

14
Q

What is glutamate?

A

The main excitatory neurotransmitter in the nervous system.

15
Q

What does glutamate do?

A

It increases the likelihood of the postsynaptic neuron firing an action potential.

16
Q

What role(s) in functioning does glutamate have?

A

It has a role in learning and memory by strengthening synaptic connections.
It also have a role in thought and movement.

17
Q

What is an inhibitory effect?

A

When the neurotransmitter decreases the likelihood of the postsynaptic neuron firing an action potential.

18
Q

What is GABA? (gamma-aminobutyric acid)

A

The main inhibitory neurotransmitter in the nervous system.

19
Q

What effect does gaba have?

A

It decreases the likelihood of the postsynaptic neuron firing an action potential.

20
Q

What role in functioning does gaba have?

A

Gamma-aminobutyric acid.

It is the main inhibitory neurotransmitter in the nervous system.

It has a role in regulating the postsynaptic activation and prevents overexcitation of neurons. GABA can reduce anxiety and also seizures.

21
Q

What is a neuromodulator?

A

A chemical molecule that has an effect on multiple postsynaptic neurons. Is longer lasting, but taking longer to activate.

22
Q

What is dopamine?

A

A neuromodulator responsible for voluntary motor movement, the experience of please and reward based learning.(which can sometimes lead to addiction)

23
Q

Where do the pathways originate from that dopamine travels along?

A

It is produced in the substantia nigra and ventral tegmental area which are both located in the midbrain.

24
Q

What affect does dopamine have on the postsynaptic neuron?

A

It can have either an excitatory or inhibitory effect depending on the type of receptor sites.

25
Q

What roles in functioning does dopamine have?

A

A role in coordingating voluntary motor movement and smooth, coordinated muscle movement.
A role in reward based learning.
Role in motivation which can lead to addiction.

26
Q

What is serotonin?

A

A neuromodulator primarily responsible for the regulation of mood and sleep.

27
Q

Where do the pathways originate that serotonin travels along?

A

The raphe nuclei which are masses of neurons in the brainstem that produce serotonin.

28
Q

What effect does serotonin have on the postsynaptic neuron?

A

It has inhibitory effects.

29
Q

What roles in functioning does serotonin have?

A

Mood regulation and stabilisation, low levels can result in depression.
Regulates the sleep wake cycle.
Other roles depending on the receptor site and the brain area.