neurons Flashcards
what is the definition of membrane potential?
potential difference between interior of a cell and interstitial fluid beyond the membrane
what is hyperpolarisation?
when the membrane potential moves away from o
what is depolarisation?
when the membrane potential moves towards 0
describe the sequence of events that lead to and follow an action potential
. if MP raised to approx -50mV, larger depolarisation occurs (AP)
. Threshold for sodium ion channles reached so they open, causing MP to move towards 0 as sodium ions diffuse into cell through volagte gated channel
. when MP reaches +35mV, sodium ion channels shut and volateg gated potassium ion channels open
. potassium ions leave cell
. overshoot occurs
how does local anaesthetic work?
blocking sodium ion channels
what is the funtion of the refractory period after an AP
neuron cannot generate another AP until 1st one has ended
what is the fucntion of myelination
increase action potential comdution speed