cell communication Flashcards
what are the 2 forms of communication between cells?
electrical amd chemical
describe electrical transmission between cells
direct contact via gap junctions which allow flow of current from cell to cell
describe the stages in chemical transmission by synapse
. impulse arrives at terminal of presynaptic cells
. transmitters released from vesicles where they diffuse into synaptic cleft
. transmitters bind to receptors on post-synaptic cell altering that cell
describe pancreatic communication
chemical sent to all parts of body via bloodstream, hormone only acts on cells with correct membrane receptor
what is a second messenger?
intracelluar signalling molecule
describe the action of steroid transmitters
lipids that can enter cell, act on receptors within the cell to form a steroid-receptor complex that acts on DNA in the nucleus to intiate protein synthses. Protein produced alters cell funtion
describe the action of peptide transmitters
cannot enter cell so bind to receptor on plasma membrane of cell activating series of reactions controlled by g-proteins, which in turn activate cAMP and calcium ions
describe the process by which a g-protein activates cAMP
. membrane receptor activates g-protein
. ATP converted to cAMP by adenyl cyclase which acyivates an enzyme which forms proteins
what is autocrine?
when chemical acts on the cell releasing it
what is paracrine?
hormones are released from cells and bind to receptor on nearby cells and affects their function
give an example of when paracrine communication is used?
inflammation
compare nerve communication to hormonal communication?
- nerve communication rapid but short lived
- hormonal communication slow but the action persists