Neurons Flashcards

1
Q

The nervous system is made of…

A

Neurons and Glia cells

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2
Q

Neurons

A

specialized cells that can receive and send electrical and chemical signals

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3
Q

Glia cells

A

Provide support functions to neurons

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4
Q

Action Potentials

A

Electrical signals that travel along the axon of a neuron

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5
Q

Neurotransmitters

A

Chemical signals that travel along the synapse and induce a change in membrane potential in the postsynaptic cell

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6
Q

Dendrites

A

Little branches off the main body of the neuron, receive neurotransmitters from other neurons

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7
Q

Synapses

A

Specialized junctions between neurons where they send and receive information

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8
Q

Axon Hillock

A

Integrates multiple signals from other neurons. Serves as a junction between body and axon

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9
Q

Axon

A

Tubelike structures that specialize in carrying signals to specialized ends are called axon terminals.

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10
Q

Nodes of Ranvier

A

Gaps in myelin sheath where the action potentials recharge as it travels down the axon

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11
Q

Types of Glia cells

A

MicroGlia, Astrocytes, Sattelite Glia, Oligodendrocytes, Schwann cells, and Ependymal cells

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12
Q

Most Brain tumors are caused by…

A

Mutated glia cells

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13
Q

Astrocytes

A
  • Provide neurons with nutrients and other substances
  • Regulate concentration of ions and chemicals in extracellular fluid
  • Form a blood-brain barrier to block toxic substances from entering
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14
Q

Sattelite Glia

A

Nutrients and structure support in Peripheral Nervous system

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15
Q

Microglia

A
  • Immune system of the central nervous system

* Scavenge and degrade dead cells and invading microorganisms

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16
Q

Oligodendrocytes

A
  • Form myelin sheaths along the axon

* One oligodendrocyte can provide a myelin sheath for multiple neurons

17
Q

Schwann Cell

A
  • Form myelin sheath in the peripheral nervous system

* A single Schwann cell provides myelin for only one axon as the entire cell surrounds the axon

18
Q

Ependymal cells

A
  • Line fluid-filled ventricles on the brain and central canal of the spinal cord
  • Help circulate cerebrospinal fluid, which serves as a cushion for the brain
19
Q

Resting phase

A

Membrane potential in a neuron that is currently not transmitting a signal

20
Q

Action Potential

A

Brief depolarization along the axon

All or nothing

21
Q

Membrane potential at rest is around

22
Q

Resting membrane potential is established by…

A

Ion channels and pumps

23
Q

Sodium-Potassium ion pump

A

Pumps in 2 K+ ions and pumps out 3 Na+ ions. Uses ATP. important for maintaining electrogradient

24
Q

Potassium Leak channel

A

Allows potassium to leak outside of the cell

25
Depolarization
Voltage-gated Na+ channels open quickly after threshold potential is reached. Sodium begins to rush into the axon, making it more positive (around 30mV)
26
Repolarization
The Voltage-gated Na+ channel shuts and remains closed. Voltage-gated K+ channels open, K+ rushes out of the axon, causing the axon to become more negative, repolarizing
27
Hyperpolarization
K+ continues to leave to the point where the axon below the resting potential
28
Reset Resting Potential
Pumps and Ion channels work to reestablish resting potential for another Action potential to fire
29
The action potential travels down the axon in...
waves
30
Why don't Action Potentials go backward?
Voltage-gated ion channels like Na+ are shut and the hyperpolarization of previous action potential prevents backward movement of action potentials
31
One node to another is called
Saltatory Conduction
32
Once an action potential reaches the end of an Axon
The end of the axon depolarizes, this causes Voltage-gated Calcium channels to open. Calcium triggers a signaling cascade that causes synaptic vesicles to fuse with the pre-synaptic membrane, which releases neurotransmitters into the synaptic cleft.
33
Excitatory Post-synaptic Potentials
Make neurons more likely to fire an action potential (depolarize)
34
Inhibitory postsynaptic potentials
Make neurons less likely to fire an action potential (hyperpolarize)
35
What gives the membrane of neurons their negative charge
The outflow of K+ ions results in the negative charge within the cell