Neuromuscular Control Flashcards
What helps to maintain the resting membrane potential?
- negatively charged cytosol
- K+ intracellularly
- Na+ and Cl- extracellularly
Alterations in resting membrane potential are how neurons and myocytes:
receive, transmit, and integrate info with themselves and other cells
Depolarizing is to:
make less negative by opening Na+ channels
Repolarizing is to:
make more negative by opening K+ channels and inactivating Na+ channels
Hyperpolarizing is to:
make more negative than threshold by K+ channels still being open and Na+ channels in resting state
What determines the velocity at which APs are propagates along cell membranes?
fiber diameter and presence of myelin
A larger fiber results in:
lower resistance so faster conduction
Presence of myelin results in:
AP skip from node to node (saltatory conduction) and speeds conduction
What are graded potentials?
potentials in post-synaptic membrane that are proportional to stimulus strength
How are graded potentials propagated? APs?
GP: ion channels
AP: voltage gated Na and K channels
Where can graded potentials occur?
any membrane region that receives sensory stimuli
What motor units are recruited first?
those with smaller neuron bodies–type I
What neurotransmitter is released at the NMJ?
Ach
What does the thalamus contain?
relay pathways from cerebellum, basal ganglia, and superior colliculus to motor cortex
What does the thalamus contribute to?
motor generation and self-monitoring