Neurologic/Psychiatric Disorders Flashcards
CSF findings in bacterial meningitis
neutrophils
high protein
low glucose
positive culture/positive gram stain
CSF findings in viral meningitis
lymphocytes
high protein
normal glucose
viral PCR may be positive
CSF findings in viral encephalitis
lymphocytes
high protein
normal glucose
viral PCR may be positive
may also see frontotemporal hemorrhage and RBCs in HSV encephalitis
CSF findings in tuberculosis meningitis
lymphocytes
high protein
very low glucose
positive for acid-fast bacilli
CSF findings in guillain-barre syndrome
no cells
high protein
normal glucose
CSF findings in multiple sclerosis
few lymhocytes
slightly high protein
normal glucose
oligoclonal bands
CSF findings in acute disseminated encephalomyelitis
lymphocytes
high protein
normal glucose
oligoclonal bands
CSF findings in subarachnoid hemorrhage
lymphocytes and many RBCs
high protein
normal glucose
xanthochromia
CSF: RBCs and no xanthochromia
traumatic tap
CSF: positive EBV PCR
highly suggestive of CNS lymphoma
CSF: oligoclonal bands
multiple sclerosis, CNS infections, or non-infectious inflammatory processes (SLE)
CSF: low glucose
bacterial or mycobacterial infections
CSF: lymphocytes
viral, fungal, or mycobacterial infection, demyelination, CNS lymphoma
normal CSF pressure
70-180 mmH2O
where olfactory nerve exits
cribiform plate
where optic nerve exits
optic canal
where oculomotor nerve exits
superior orbital fissure
where trochlear nerve exits
superior orbital fissure
where trigeminal V1 exits
superior orbital fissure
where trigeminal V2 exits
foramen rotundum
where trigeminal V3 exits
foramen ovale
where abducens nerve exits
superior orbital fissure
where facial nerve exits
internal auditory meatus
where vestibulocochlear nerve exits
internal auditory meatus
where glossopharyngeal nerve exits
jugular foramen
where vagus nerve exits
jugular foramen
where accessory nerve exits
jugular foramen
where hypoglossal nerve exits
hypoglossal foramen
pupillary reflex
CNII (afferent fibers) and CNIII (efferent fibers)
shine line in each pupil and observe reaction and accomodation
oculocephalic (doll’s eyes) reflex
CNVIII (afferent) and CN III, IV, and VI (efferent) forcibly turn head horizontally and vertically and observe for conjugate eye movement in opposite direction
gag reflex
CNIX (afferent) and CN X, XI (efferent)
stimulate posterior pharynx with cotton tip and observe for gag
biceps reflex
C5
brachioradialis reflex
C6
triceps reflex
C7
finger flexor reflex
C8/T1
patellar reflex
L4
hip adductor reflex
L3
ankle jerk reflex
S1
PCA stroke
occipital cortex, visual cortex
contralateral hemianopsia with macular sparing
amygdala lesion
kluver-bucy syndrome: hyperorality, hypersexuality, disinhibited behavior
friedreich ataxia
progressive ataxia that affects ares more than legs, onset usually in childhood, impaired vibration and position sense
slapping gait
dorsal column neuropathy
vitamin B12 deficiecny, tabes dorsalis
waddling gait
hip-girdle weakness
muscular atrophy, proximal myopathy, muscular dystrophy
simple v. complex seizures
complex seizures have a loss of consciousness, simple seizures do not
best predictor of prognosis in astrocytomas
degree of anaplasia
first line therapy for delirium in the elderly
haloperidol
prion disease that may cause myoclonus
creutzfeldt-jakob disease
children under 7 who have a wide array of seizure types accompanied by mental retardation
lennox-gastaut syndrome
progression from absence seizures beginning age 10 to myoclonic seizures around age 15 to tonic-clonic seizures around age 16, may be worsened by sleep deprivation
juvenile myoclonic epilepsy
cushing’s triad for intracranial pressure
bradycardia, bradypnea, hypertension
subarachnoid hemorrhage suspected, CT is equivocal, next step
lumbar puncture
most common etiologies of bacterial meningitis in adults < 60
streptococcus pneumoniae
neisseria menigitidis
haemophilus influenzae
treatment for various side effects of typical antipsychotics
acute dystonia: benztropine
akathisia: benzodiazapine
neuroleptic malignant syndrome: bromocriptine
tardive dyskinesia: irreversible, stop offending agent
ipsilateral motor and proprioception loss and contralateral pain loss below the level of the lesion
hemsection of cord
burning pain and paralysis in upper extremities, secondary to forced hyperextension type of injury to the neck
central cord syndrome
burst fracture of vertebra characterized by total loss of motor function below the level of the lesion, loss of pain and temperature bilaterally
anterior cord syndrome
innervation of anterior thigh muscles
femoral nerve
nerve that provides sensation to the medial leg (calf)
saphenous branch of femoral nerve
innervation of medial thigh muscles
obturator nerve (adduction)
innervation of posterior compartment of leg (calf), plantar muscles of foot
tibial nerve (flexion)
innervation to anterolateral leg, dorsum of foot
fibular nerve (extension)
vascular supply of midbrain
basilar artery
vascular supply of pons
basilar artery and AICA
vascular supply of medulla
PICA
dorsal column function
vibration and proprioception
spinothalamic tract function
pain and temperature
corticospinal tract function
voluntary movement
loss of spinal cord function except dorsal columns are intact
anterior spinal artery syndrome
ventral horn and ventral white commissure affected, flaccid paralysis at level of lesion, loss of pain and temperature one level below the lesion
syringomyelia
bilateral loss of vibration and discrimination and bilateral spastic paresis affecting legs before arms
vitamin B12 deficiency
contralateral lower extremity and trunk weakness
anterior cerebral artery stroke
contralateral face and upper extremity weakness and decreased sensation, bilateral visual abnormalities, aphasia or neglect
middle cerebral artery stroke
contralateral visual abnormalities
posterior cerebral abnormalities
focal motor or sensory deficits, loss of coordination, difficulty speaking
lacunar arteries
cranial nerve abnormalities, contralateral full body weakness and decreased sensation, vertigo, loss of coordination, difficulty speaking, visual abnormalities, coma
basilar artery
measures on the glascow coma scale
eye opening (4), verbal response (5), motor response (6)
long-term treatment for mania
lithium, lamotrigine, olanzapine, or quetiapine
second line: valproate, aripiprazole
treatment for bedwetting
first line: desmopressin
second line: imipramine (more side effects)
treatment for adjustment disorder
psychodynamic psychotherapy
acute treatment for panic attack
short-term benzo: alprazolam
long-term treatment for panic attack
SSRI
second line: long-acting benzo (clonazepam, diazepam)
treatment for ADHD
methylphenidate, atomoxetine
second line: bupropion, alpha-agonists, TCAs
treatment for tourette’s syndrome
fluphenazine, pimozide, tetrabenazine
second line: haloperidol
autism-like symptoms that develop after age 3
childhood disintegrative disorder
want to hit your wife but you hit a chair instead
displacement
unfaithful husband accuses his own wife of being unfaithful
projection
IV drug use gets hepatitis C through needles and blames the community for not having adequate control over hepatitis C
distortion
patient rescued from a burning building and denies any memory of the event
dissociation
feelings of shyness, inferiority
desire to make friends overcome by fear of rejection
avoidant personality disorder
excessive need to be cared for, submissive with loved ones
dependent perosnality disorder
magical thinking
schizotypal
side effects of lithium in utero
ebstein’s anomaly in first trimester
goiter and neuromuscular dysfunction in later trimesters
injectable anti-psychotics
haloperidol decanoate (1-2 times a month) fluphenazine decanoate (twice a month) risperidone depot (twice a month) palpieridone depot (once a month)