Neurocognitive Disorders - Delirium Flashcards

1
Q

delirium settings

A

Commonly seen on inpatient medical/surgical units and in extended care facilities

1/3 of hospitalized medical patients older than 70

15% of patients older than 70 presenting to ED

Under-Recognized by health care professionals

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2
Q

delirium

A

a MEDICAL ILLNESS, an ACUTE confusional state, caused by the direct physiological consequences of a general medical condition (typically multiple fx).

  • often (not always) accompanied by perceptual/emotional disturbances.
  • usu lasts days-weeks, may persist
  • most common complication of hospitalized elderly patients
  • source of patient and caregiver distress
  • inc morbidity/mortality/institutionalization/dementia
  • inc health care costs (inc length of stay)
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3
Q

delirium clinical features

A
  • acute onset
  • fluctuating course
  • inattention
  • disorganized thinking
  • altered level of consciousness
  • cognitive deficits
  • perceptual disturbances
  • psychomotor disturbances (hypO or hypER active)
  • altered sleep-wake cycle
  • emotional disturbance
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4
Q

delirium risk fx

A
Dementia
Older age
Immobility
Sensory impairment (visual/hearing)
Dehydration/malnutrition
Alcohol abuse
Treatment with many drugs (esp. psychoactive)
Underlying severe medical illness (renal, hepatic, cardiac, etc.)
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5
Q

delirium precipitating factors (drugs)

A
Benzodiazepines
Narcotics
Anticholinergics*
Steroids
Elevated levels (e.g. digoxin)
Anticonvulsants
Alcohol/drug withdrawal

elderly are sensitive

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6
Q

anticholinergic side effects

A

RED as a BEET - flushed skin
DRY as a BONE - dry skin/membranes, urinary retention
BLIND as a BAT - mydriasis
HOT as a HARE - fever
MAD as a HATTER - mental status change

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7
Q

precipitating fx of delirium

A
Infections/fever 
Post-operative states 
Metabolic disorders 
Cardiovascular disorders
Hypoxia
Sleep deprivation
Use of physical restraints or catheters
CNS disorders (subdural hematoma)
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8
Q

delirium EEG findings

A

usually diffuse slowing

delirium tremens –> low-voltage fast-activity waves

hepatic encephalopathy - triphasic waves

May help distinguish atypical delirium from a primary psychiatric disorder

Can ID occult seizure disorder

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9
Q

Longer delirium duration and severity associated with increased incidence of _____

A

Longer delirium duration and severity associated with increased incidence of DEMENTIA

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10
Q

Delirium prevention

A

Address risk fx

Provide orienting communication (use family)

Encourage early mobilization

Use visual and hearing aids

Prevent dehydration

Provide uninterrupted sleep time

Prophylactic meds (?) – benzos to prevent delirium tremens in alc w/d, antipsychotics to prevent post-operative delirium

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11
Q

delirium management

A

medical eval/stabilization

remove physiologic stressors

some may not be able to fully stabilize

quiet room, lights in AM, dark PM

avoid xs sensory stim

orientation cues (clock, pics)

hearing aids, eyeglasses

exercise

trained sitters/nurse

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12
Q

pharmacologic management of delirium

A

antipsychs may help decrease delirium severity/duration

- can decrease the effects of irreversible dementia that may result

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13
Q

cholinesterase inhibitors for delirium

A

trials have been disappointing

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14
Q

delirium is characterized by which NT changes?

A

increased DA, decreased ACh

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15
Q

T/F

When the underlying medical abnormality causing delirium is successfully addressed, the associated cognitive difficulties will always fully resolve.

A

Ideally, true.

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16
Q

Patients with dementia are more likely to experience delirium than patients without dementia.

A

True.

Dementia is a risk factor for delirium. Some patients with dementia do not return to their baseline level of functioning after an episode of delirium.

The longer the duration of the delirium, the increased risk of dementia.

17
Q

Which class of medication is most likely to be helpful for severely agitated patients with delirium?

A

antipsychotics