Neuro V Flashcards

1
Q

werdnig hoffman disease

A

congenital - degeneration of anterior horns SC
auto rec
spinal muscular atrophy

LMN lesion only

destroy anterior horn
flaccid paralysis

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2
Q

multiple sclerosis

A

demyelination

loss white matter cervical region

nystagmus, intention tremor, etc.

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3
Q

AML

A

UMN and LMN dosorder

no sensory or oculomotor defect

defect - SOD 1

fasisculation with atrophy and weak hands

riluzole - increased survival - by decrease presynpatic glutamate relase

aka lou gehrig

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4
Q

riluzole

A

glutamate antagonist

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5
Q

occlusion of anterior spinal artery

A

spare dorsal column and lissauer tract

upper thoracic ASA - watershed area

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6
Q

tabes dorsalis

A

tertiary syphilis

demyelination - dorsal columns and roots

loss sensation/proprioception
progressive sensory ataxia

absent DTR and romberg sign

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7
Q

syringomyelia

A

B/L pain and temp - C8-T1

with chiari I malformation

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8
Q

vit B12 deficiency

A

subacute combined degeneration of SC

demyelination dorsal column, lateral corticospinal tract, spinocerebellar tract

ataxic gait
paresthesia
impaired position and vibration sense

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9
Q

poliomyelitis

A

poliovirus
fecal oral

replicate- oropharynx and small intestine

destruction anterior horn of spinal cord - LMN death

sx - weak, hypotonic, flaccid paralysis, fasiculation, hyporeflex, muscle atrophy

CSF high WBC and high protein

virus in stool and throat

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10
Q

friedreich ataxia

A

CH 9 auto rec GAA repeat
-frataxin protein - iron binding

impair mito fxn

degeneration multi tracts of SC

  • muscle weak, loss DTR, vib sense, proprio
  • staggering gait, falling, nystagmus
  • hammer toe, pes cavus
  • diabetes mellitus

cause of death - hypertrophic cardiomyoapthy

with kyphoscoliosis

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11
Q

brown sequard syndrome

A

hemisection of SC

UMN sign below lesion I/L

I/L loss tactile, vibration, proprioception

C/L - pain and temp below lesion

above T1 - may see horner syndrome

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12
Q

L4 dermatome

A

kneecap

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13
Q

T10 dermatome

A

belly button

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14
Q

T4 dermatome

A

nipple

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15
Q

S2,3,4 dermatome

A

erection and sensation of penile and anal zone

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16
Q

L1 dermatone

A

inguinal ligamnet

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17
Q

T7 dermatome

A

xiphoid

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18
Q

C2 dermatome

A

skull cap

19
Q

C3 dermatome

A

high collar

20
Q

C4 dermatome

A

low collar

21
Q

anal wink

A

S3/4

22
Q

cemaster reflex

A

L1-2

23
Q

tricep reflex

A

C7

24
Q

bicep reflex

A

C5

25
Q

patellar reflex

A

L4

26
Q

achilles reflex

A

S1

27
Q

moro refle

A

abduct/extend arm when startled

28
Q

sucking reflex

A

touch roof mouth

29
Q

plantar reflex

A

dorsiflex large toe and fan other toes

babinski - see this in adult - UMN lesion

30
Q

galant reflex

A

stoke side of spine

lateral flexion toward stimuli

31
Q

CN IV

A

trochlear - arise dorsally and immediately decussates

32
Q

cranial nerves medial on brainstem

A

3, 4, 6, 12

33
Q

superior colliculi

A

vertical gaze

34
Q

inferior colliculi

A

auditory

35
Q

parinaud syndrome

A

loss conjugate vertical gaze

lesion - superior colliculi

36
Q

optic canal

A

CN 2
ophthalmic artery
central retinal vein

37
Q

superior orbital fissure

A

CN 3, 4, 5a, 6

ophthlamic vein

38
Q

foramen rotundum

A

5b

39
Q

foramen ovale

A

5c

40
Q

foramen spinosum

A

middle meningel a

41
Q

internal auditory meatus

A

CN 7,8

42
Q

jugular foramen

A

CN 9, 10, 11

jugular vein

43
Q

hypoglossal canal

A

CN 12

44
Q

foramen magnum

A

spina root CN 11
brain stem
vertebral arteries