Neuro V Flashcards
werdnig hoffman disease
congenital - degeneration of anterior horns SC
auto rec
spinal muscular atrophy
LMN lesion only
destroy anterior horn
flaccid paralysis
multiple sclerosis
demyelination
loss white matter cervical region
nystagmus, intention tremor, etc.
AML
UMN and LMN dosorder
no sensory or oculomotor defect
defect - SOD 1
fasisculation with atrophy and weak hands
riluzole - increased survival - by decrease presynpatic glutamate relase
aka lou gehrig
riluzole
glutamate antagonist
occlusion of anterior spinal artery
spare dorsal column and lissauer tract
upper thoracic ASA - watershed area
tabes dorsalis
tertiary syphilis
demyelination - dorsal columns and roots
loss sensation/proprioception
progressive sensory ataxia
absent DTR and romberg sign
syringomyelia
B/L pain and temp - C8-T1
with chiari I malformation
vit B12 deficiency
subacute combined degeneration of SC
demyelination dorsal column, lateral corticospinal tract, spinocerebellar tract
ataxic gait
paresthesia
impaired position and vibration sense
poliomyelitis
poliovirus
fecal oral
replicate- oropharynx and small intestine
destruction anterior horn of spinal cord - LMN death
sx - weak, hypotonic, flaccid paralysis, fasiculation, hyporeflex, muscle atrophy
CSF high WBC and high protein
virus in stool and throat
friedreich ataxia
CH 9 auto rec GAA repeat
-frataxin protein - iron binding
impair mito fxn
degeneration multi tracts of SC
- muscle weak, loss DTR, vib sense, proprio
- staggering gait, falling, nystagmus
- hammer toe, pes cavus
- diabetes mellitus
cause of death - hypertrophic cardiomyoapthy
with kyphoscoliosis
brown sequard syndrome
hemisection of SC
UMN sign below lesion I/L
I/L loss tactile, vibration, proprioception
C/L - pain and temp below lesion
above T1 - may see horner syndrome
L4 dermatome
kneecap
T10 dermatome
belly button
T4 dermatome
nipple
S2,3,4 dermatome
erection and sensation of penile and anal zone
L1 dermatone
inguinal ligamnet
T7 dermatome
xiphoid