Neuro IX Flashcards
glioblastoma multiforme
grade IV astrocytoma
highly malignant - 1 year survival
cerebral hemispheres
GFAP astrocyte stain
pseudopalisading pleomorphic tumor cell
meningioma
B9 brain tumor
convexity of hemisphere - near surface
from arachnoid cells
may have dural atta hment
tx - resection
spindle cell concentrically arranged in whorled pattern
also psammoma bodies
hemangioblastoma
cerebellar
with VHL syndrome - with retinal angioma
produce EPO - 2ndary polycythemia
close arranged thin wall caps with minimal intervening parenchyma
schwannoma
at cerebellopontine angle
schwann cell origin
S-100 positive
often CN VIII
oligodendroglioma
rare slow growing
in front lobe
chicken wire cap pattern
oligodendrocyte fried egg appearance
pituitary adenoma
often PRLoma
bitemporal hemianopia
pilocytic astrocytoma
low grade
well circumscribed
posterior fossa of children
GFAP positive
B9 good prognosis
rosenthal fibers
medulloblastoma
malignant cerebellar tumor
compress 4th ventricle - hydrocephalus
drop mets to SC
homer wright rosettes
solid - small blue cells
ependymoma
ependymal tumor cell - 4th ventricle
hydrocephalus
poor prognosis
perivascular rosettes
blepharoplasts - basal ciliary bodies
craniopharyngioma
B9 childhood tumor
remnant of rathke pouch - ant pituitary
tooth enamel like
falx cerebri herniation
anterior cerebral a
transtentorial hernation
downard
displace brainstem
rupture basilar artery brnaches
often fatal
uncal hernation
medial temporal lobe
compress I/L CN III -3 - blown pupil and down and out gaze
I/L PCA lesion - contralateral homonymous hemianopia
cerebellar herniation
into foramen magnum
brainstem lesion - coma and death