Neuro - Tumours Flashcards
what is hydrocephalus?
accumulation of CSF in the ventricles/around the brain
difference between non communicating and communicating hydrocephalus?
non communicating - obstruction in ventricles
communicating - blocked outside ventricles
features of normal pressure hydrocephalus?
wet
wacky
wobbly
features of hydrocephalus?
reduced consciousness papilloedema headache N+V neck stiffness
features of hydrocephalus in kids?
tense fontanelles
increased head size
downward deviation of eyes
what happens in a subfalcine herniation?
cingulate gryus displaces under falx cerebri (midline)
ischaemia to motor and sensory cortex
what happens in a tentorial herniation?
temporal lobe herniates over tentorium cerebelli
CN III palsy (down and out, blown pupil)
what happens in a cerebellar/tonsillar herniation?
tonsils herniate through foramen magnum
respiratory centre in medulla compromised
what happens in a transcalvarial herniation?
swollen brain herniates through any skull defect
where is CSF formed?
choroid plexus of the lateral ventricles
route of CSF?
choroid plexus of lat ventricles -> 3rd -> cerebral aqueduct -> 4th -> Subarachnoid space
what absorbs CSF?
arachnoid granules
what can cause a non communicating hydrocephalus?
meningitis
SAH
layers of spinal cord?
dura
arachnoid
pia
Ix for hydrocephalus?
US <6 months/MRI
LP for communicating ONLY
Tx for hydrocephalus?
treat cause
VP shunt
what genetic condition is associated with mengiomas?
NF2
where do meningiomas come from? do they become malignant?
mesenchymal cells in the meninges
rarely invade
Ix for SOL?
CT
T1/2 weighted MRI
features of a frontal lobe tumour?
personality change
brocas/wernicke’s
hemiparesis
features of a temporal lobe tumour?
dysphasia
amnesia
homonymous hemianopia
features of a parietal lobe tumour?
sensory loss
dysphasia
commonest malignant brain tumour in kids?
medulloblastoma
how does medulloblastoma commonly present? why?
raised ICP
occur in midline cerebellum so blocks CSF flow
most common malignant brain tumour in adults? 2nd most common?
glioblastoma
oligodendroglial