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Pharm > Neuro buzz > Flashcards

Neuro buzz Flashcards

1
Q

opioid receptor activation

A

closes Ca2+ channels

opens K+ channels

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2
Q

hepatotoxicity

acute angle closure glaucoma

A

duloxetine

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3
Q

constriction of visual field, retinal damage

A

vigabatrin

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4
Q

increased BP

cardiotoxicity

A

amphetamines

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5
Q

opioid with CYP interactions

A

fentanyl

somewhat-codeine, hydrocodone, oxycodone

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6
Q

TCA + MOAI

A

serotonin syndrome

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7
Q

reverses DAT

A

amphetamines

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8
Q

not taken with MAOI

A

meperidine

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9
Q

transient visual hallucinations

A

cyclobenazaprine

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10
Q

warfarin

A

phenytoin

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11
Q

articaine use

A

dentistry

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12
Q

what’s so different about meperidine and dextromethorphan?

A

they also have NDMA blocking activity

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13
Q

methemoglobinemia

A

prilocaine

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14
Q

pt with closed angle glaucoma

A

no levodopa

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15
Q

opioid usually used with anesthesia or surgery

A

fentanyl

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16
Q

meperidine CI

A

renal failure

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17
Q

mepivicaine uses

A

peripheral

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18
Q

social anxiety DOC

A

paroxetine

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19
Q

inhibition of ejaculation

A

chlorpromazine

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20
Q

Addison’s CI

A

opioid

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21
Q

5 HT antagonist

A

trazadone

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22
Q

interferes with Ca release at NMJ

A

dantrolene

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23
Q

how do lithium and sodium compete?

A

for reabsorpiton

NOT excretion

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24
Q

hyperpyrexia

A

cocaine

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25
Q

used for bipolar d/o, migraine prophylaxis

A

valproic acid

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26
Q

prolactin effect of dopamine agonist

A

decreased release

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27
Q

caution with history of seizures or CHF

A

amantadine

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28
Q

inhibits sulfonamides

A

PABA from procaine

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29
Q

truncal rigidity

A

opioids

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30
Q

tx for depression associated with bipolar

A

lurasidone

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31
Q

ropivicaine uses

A

peripheral

epidural

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32
Q

worst anesthetic for CV effects

A

bupivicaine

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33
Q

analegesia (LA) for post-op pain

A

bupivicaine

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34
Q

similar to but more sedating than clozapine

A

quitiapine

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35
Q

excessive sweating on lithium

A

lithium toxicity

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36
Q

CYP inhibitor

A

valproic acid

fluoxetine/paroxetine

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37
Q

CI for meperidine (not meds)

A

renal failure

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38
Q

OCD DOC

A

paroxetine

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39
Q

meperidine + what= serotonin syndrome

A

phenelzine
selegiline
lineozlid

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40
Q

LA not used with cardiac/respiratory dz

A

prilocaine

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41
Q

antidepressants+lithium

A

mania

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42
Q

agranulocytosis

A

clozapine

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43
Q

increased prolactin

A

risperidone

44
Q

mydriasis

tachycardia

A

meperidine

45
Q

inducers of CYPs

A

barbituates
phenytoin
carbamazepine
carisoprodol

46
Q

Zyprexia diabetes

A

olanzapine

47
Q

prolonged QT

A

ziprasidone

48
Q

impairs BG in DM

A

fluoxetine

49
Q

TdP

A

TCA OD

50
Q

long duration with sensory>motor

A

bupivicaine

51
Q

sudden sleep during the day

A

pramipexole

ropinirole

52
Q

elevated ICP

A

opioid

53
Q

lidocaine use

A

infiltration

spinal (not really)0

54
Q

long duration but short onset of action LA

A

tetracaine

55
Q

atomoxetine MOA

A

SNRI

56
Q

tx for Parkinson’s pt with psychosis

A

clozapine
quetiapine
aripiprazole

57
Q

inhibits reuptake of DA

A

buproprion

58
Q

agonist at kappa

partial agonist at mu

A

pentazocaine/naloxone

59
Q

GABA agonist mm relaxer

A

baclofen

60
Q

LA for pruritus

A

benzocaine

61
Q

malignant hyperthermia

A

general anesthetics

62
Q

elevated ICP

A

opioids

63
Q

SE of baclofen

A

drowsiness

mm weakness

64
Q

anesthetic that is not weak base

A

benzocaine

65
Q

neuroleptic malignant syndrome

A

antipsychotics

66
Q

valproic acid CI

A

liver dz

67
Q

weak mu agonist

inhibit reuptake of NE, 5HT

A

tramadol

68
Q

GABAb receptor

A

Gi linked
hyperpolarizes neurons
(Baclofen)

69
Q

lens/corneal deposits

A

chlorprozamine

70
Q

procaine use

A

infiltration

71
Q

MAOI+ opioid

A

hyperpyrexic coma

72
Q

decreased esophageal motility

A

aripiprazole

73
Q

anticonvulsant used for pruritus and restless leg syndrome

A

pregabalin

74
Q

meprobamate

A

carisoprodol metabolite

75
Q

opioid that also blocks NMDA

A

methadone

76
Q

tolerance to antiseizure effect

A

clonazepam

77
Q

Tourette’s

A

ziprasidone

78
Q

anesthetic with highest rate of clearance

A

prilocaine

79
Q

what do you give with apomorphine?

A

antiemetic

80
Q

tramadol+antidepressants

A

seizures

81
Q

too much lithium

A

hyponatremia

82
Q

most cardiotoxic LA

A

bupivicaine

83
Q

levodopa+MAOI

A

HTN crisis

84
Q

affects motor nerves

A

etidocaine

85
Q

MOAI+ dextromethorphan

A

serotonin syndrome

86
Q

inhibits its own metabolism at low doses

A

valproic acid

87
Q

abnormal dreams

HA

A

suvorexant

88
Q

TCA + SSRI

A

compete for metabolism=toxic levels of TCA

89
Q

not used for IV regional anesthesia

A

bupivicaine

90
Q

blocks presynaptic alpha 2 receptors

A

mirtazapine

91
Q

livedo reticularis

A

amantadine

92
Q

anticonvulsant with sedative properties

A

pregabalin

93
Q

LA toxic to neonate

A

mepivicaine

94
Q

SIADH

A

TCAs

95
Q

active PUD

A

no levodopa

96
Q

antipsychotic with no histamine/muscarinic effects

A

lurasidone

97
Q

inhibits DA reuptake

A

cocaine

98
Q

tramadol + what= serotonin syndrome

A

TCA
SSRI
MAOI

99
Q

death from liver dz

A

tolcapone

100
Q

low sodium

A

lihtium toxicity

101
Q

persistent paresthesias

A

articaine

102
Q

Parkinson’s drug used for restless leg syndrome

A

ropinirole

103
Q

block DA in nigrostiatal system

A

EPS

104
Q

malignant melanoma

A

no levodopa

105
Q

tyramine–>HTN crisis

A

MAOIs

Pharm (10 decks)

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