Exam other Flashcards

1
Q

SE of promethazine

A

anticholinergic

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2
Q

which second gen antihistamine for liver dz?

A

certirizine

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3
Q

which second gen antihistamine for kidney dz?

A

loratadine or fexofenadine

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4
Q

azelastine

A

nasal H1 antagonist

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5
Q

what is always combined with an ICS?

A

LABA

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6
Q

decreases fatigue of diaphragm

A

theophylline

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7
Q

issue with theophylline

A

narrow therapeutic range

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8
Q

SE of leukotriene inhibitors

A

sleepiness
sore throat
URI

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9
Q

drug for severe allergic asthma

A

omalizumab

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10
Q

drug for asthma with eosinophilia

A

benralizumab

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11
Q

thromboxane

A

vasoconstrictor

platelet aggregation

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12
Q

prostacyclins

A

vasodilation

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13
Q

rate limiting step of prostaglandins

A

release of arachidonic acid

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14
Q

low dose ASA: uric acid?

A

decreases excretion

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15
Q

high dose ASA: uric acid?

A

increases excretion

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16
Q

ASA elimination

A

low dose: first order

high does: zero order

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17
Q

SE of ASA

A

GI
kidney damage
resp alkalosis–> resp/metabolic acidosis

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18
Q

celecoxib SE

A

CV

19
Q

ketorolac unique

A

post op analgesia

no longer than 5 days

20
Q

magnesium

A

diarrhea

21
Q

aluminum

A

constipation

22
Q

cimetidine unique

A

anti testosterone

inhibits cyp

23
Q

omeprazole unique

A

drug interactions with clopidegrel

24
Q

SE of PPI

A

decreased Mg/Ca absoorption
increased PNa risk
decreased B12

25
Q

Parkinson’s like sxs

A

metoclopramide

26
Q

metoclopramide CI

A

pregnancy

27
Q

senna

A

irritate, stimulate GI tract

28
Q

lactulose

A

cirrhosis to decrease ammonia

29
Q

given to decrease ammonia

A

lactulose

30
Q

colonoscopy prep

A

polyehylene glycol

31
Q

laxatives that can be used chronically

A

lubiprostone

linaclotide

32
Q

lubiprostone MOA

A

open Cl-channels

33
Q

linaclotide MOA

A

increase Cl- through CFTR

34
Q

pepto CI

A

children

allergic to ASA

35
Q

micophenolate mofetil SE

A

rash

36
Q

colchicine MOA

A

inhibits microtubular system

37
Q

SE of colchicine

A

diarrhea

38
Q

XOI + 6MP

A

increased effect of 6MP

39
Q

XOI + 5FU

A

decreased effect of 5FU

40
Q

SE of XOI

A

vasculitis
agranulocytosis
hypersensitivity

41
Q

TLS

A

rasburicase

42
Q

kidney stone worry

A

uricosuric agents- probenacid or lesinurad

43
Q

gangrene

A

ergots

44
Q

drugs for migraine prophylaxis

A
valproic acid 
propranolol
verapamil
amitriptyline
venlafaxine
ACE-I/ARB
topiramate
botox
antibodiesx2