Neuro Flashcards

1
Q

Causes of dementia

A
alzheimers
chronic ETOH use
huntingtons chorea
parkinsons
hypothyroid
pernicious anemia
depression
normal pressure hydrocephalus
bismuth poisoning
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2
Q

ETOH use dementia

A

malnutrition and thiamin deficiency

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3
Q

Parkinsons etiology and tx

A

depletion of dopamine –> exaggerated ACh effect

Tx: anticholinergic therapy for tremors/ cholinesterase inhibitors (donepezil, rivastigamine, galantamine)

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4
Q

Huntingtons dz

A

dementia, chorea

autosomal dominant

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5
Q

Reversible causes of dementia

A
hypothyroid
pernicious anemia
depression
normal pressure hydrocephalus
bismuth poisoning
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6
Q

Most sensitive test for B12 deficieny

A

serum methylmalonic acid (mma)

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7
Q

Normal pressure hydrocephalus presentaion

A

dementia
abnormal gait
urinary incontinence/urgency

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8
Q

Cerebellar disease findings

A

intention tremor
nystagmus
ataxia
dysmetria

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9
Q

Impaired cerebellar fxn can be caused by

A
multiple sclerosis
stroke
midbrain tumor
mercury poisoining
Wilson's disease
hereditary cerebellar degeneration
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10
Q

Familial (essential) tremor cause, presentation and tx

A
  • autosomal dominant inheritance
  • intention and postural tremor w/ otherwise normal exam
  • propranolol
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11
Q

Myasthenia gravis etiology, presentation, diagnosis

A
  • autoimmune disorder
  • variable weakness of skeletal muscles
  • present of anti-acetylcholine receptor antibody, dx established by response to short acting anticholinesterase
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12
Q

CRP used to:

A
  • assess rick for recurrent ischemic events after CABG or PCI
  • Predict future coronary events or stroke
  • monitor RA, giant cell arteritis, PMR
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13
Q

Antiphospholipid antibody (APA) syndrome

A
  • can be primary or associated with SLE
  • increased risk of thrombosis
  • spontaneous abortion in first trimester
  • lifelong anticoagulation
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14
Q

Amaurosis fugax

A

transient, monocular loss of vision for 1-2 mins due to ipsilateral carotid atherosclerotic disease causing retinal emboli

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15
Q

Vertebrobasilar artery insufficiency manifestation

A

impaired speech, double or blurred vision, vertigo, ataxia, weakness

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16
Q

Positive neuro symptoms

A

Irritated nerve

  • Sensory: burning, tingling, visual hallucination
  • Motor: muscle jerking, repetitive rhythmic mvmt
  • Autonomic: hyperhydrosis
17
Q

Negative neuro symptoms

A

Nerve not functioning

  • Sensory/Motor: weakness, loss of sensation, visual loss
  • Autonomic:impotence, anhydrosis, lightheadedness
18
Q

Causes of Bell’s palsy

A

mono, lyme dz, sarcoidosis

1/2 cases unknown but thought to be viral related

19
Q

CN VII fxn

A

Facial nerve

  • close eyes, frown, wrinkle forehead, smile
  • salivary glands
  • taste on anterior 2/3 tongue
  • sensory fibers to external ear
20
Q

Bell’s palsy vs central CN VII palsy

A

BP- unable to wrinkle forehead on affected side

CN VII- inability to tightly close eyes but can wrinkle forehead

21
Q

CN V

A

Sensory and motor

- motor fxn to close jaw and move side to side

22
Q

Myasthenia gravis effect on eyes

A

abnormal EOM and ptosis but pupil size always normal

23
Q

Primary CN III palsy vs DM related CN III palsy

A

Primary- abnormal EOM, lateral deviation of eye and dilated pupil
DM- pupil usually normal

24
Q

B12 deficiency manifestations

A

vibratory and proprioception loss initially
progresses to ataxia and weakness
dementia

25
Q

Lyme dz and cranial nerve

A

can affect any but most common VII

26
Q

DM and CN involement

A

most common causes palsy of CN III, IV, VI (EOM)

pupil size remains normal

27
Q

DM autonomic and sensory neuropathy

A

Autonomic- orthostatic hypotension, gastroparesis, retrograde ejaculation
Peripheral- sensorimotor, N/T/B in feet, loss of vibratory, proprioceptive, light touch, and temp sensations

28
Q

wenicke’s encephalopathy manifestations

A

encephalopathy: confusion
oculomotor: eye mvmt disorder
ataxia: due to peripheral neuropathy, cerebellar degeneration, and vestibular degeneration