Endo Flashcards
1
Q
Causes of hypothyroidism
A
autoimmune
lithium
amiodarone
RAI
2
Q
Pheochromocytoma etiology and tx
A
- benign tumor on adrenals
- HTN, hypokalemia
- surgical removal
3
Q
Addison’s disease findings and diagnostic testing
A
- hyperpigmentation, hyponatremia, hyperkalemia
- Cosyntropin stimulation test (synthetic ACTH)
4
Q
Hypoglycemia clinical manifestations
A
Autonomic: tremors, sweating, palpations, hunger, paresthesias
Neuroglycopenic: confusion, fatigue, seizure, coma
5
Q
Myasthenia gravis antibody
A
Ab to acetylcholine receptor (only affects skeletal muscle)
6
Q
Graves dz
A
-autoimmune, TSH receptor Ab
hyperthyroidism, exophthalmos, pretibial myxedema, periorbital and conjunctival edema
7
Q
Causes of cushing syndome
A
- exogenous glucocorticoid meds
- Cushing dz: pituitary adenoma
- adrenal hyperplasia, adenoma, carcinoma
- ACTH secretion secondary to small cell lung ca
8
Q
Addison’s dz causes, lab findings, presentation
A
- Primary adrenal insufficiency: autoimmune or infectious (HIV, TB, fungal)
- LOW plasma cortisol
- HIGH ACTH
- HYPOnatremia, HYPERkalemia
- weight loss, anorexia, hyperpigmentation, weakness, orthostatic hypotension
9
Q
Addison’s dz diagnosis
A
cosyntropin test
10
Q
Secondary adrenal insufficiency causes, lab findings, presentation
A
- pituitary tumor, post surgical, or post radiation
- LOW ACTH and no hyperkalemia
- Symptoms the same as primary except NO hyperpigmentation
