NEURO 17 Flashcards
Medial Preoptic Hypothalamic Nuclei
GnRH (preoptic)
Paraventricular Hypothalamic Nuclei
oxytocin (anterior)
Supraoptic Hypothalamic Nuclei
ADH (anterior)
Anterior Hypothalamic Nuclei
Cools, parasympathetic, lesions cause insomnia (anterior)
Suprachiasmatic Hypothalamic Nuclei
Masterclock (anterior)
Dorsomedial Hypothalamic Nuclei
GI tract, savage and obesity w/ stimulation (middle)
Ventromedial Hypothalamic Nuclei
Satiety, savage and obesity w/ destruction (middle)
Arcuate Hypothalamic Nuclei
Releasing hormones for anterior pituitary (middle)
Posterior Hypothalamic Nuclei
Heats, sympathetics, lesions cause hypersomnia (posterior)
Lateral Hypothalamic Nuclei
Hungry destruction results in starvation, causes decrease in weight and food and water intake (posterior)
Mammillary Hypothalamic Nuclei
Lesions cause Wernike’s (posterior)
Poikilothermia
Temperature varies w/ environment, caused w/ bilateral lesions to Posterior Hypothalamic Nuclei
Posterior portion of hypothalamus
Mammillary bodies
Bulge between optic chiasm and mammilary bodies
Tuber cinereum (gray protuberance)
Pituitary fossa bounded by ___ which form ____
Anterior and posterior clinoid processes = sella turcica
4 major regions of hypothalamic nuclei
Preoptic
Anterior (supraoptic)
Middle (tuberal)
Posterior (mammillary)
Hippocampal formation projects to mammillary bodies via the
fornix
Mammillary bodies project via the ___ tract to _____
mammillothalamic tract
anterior thalamic nucleus
Anterior thalamic nucleus projects to limbic cortex in _____
cingulate gyrus
Amygdala has reciprocal connections w/ hypothalamus via ____ and ____
stria terminalis
ventral amydalofugal pathway
Hypothalamic releasing factors for ACTH
CRH, vasopressin
Hypothalamic releasing factors for TSH
TRH
Hypothalamic inhibitory factors for TSH
GIH, somatostatin
Hypothalamic Releasing factors for GH
GHRH, ghrelin
Hypothalamic Inhibitory factors for GH
GIH, somatostaatin
Hypothalmic releasing factors for Prolactin
TRH, PRF
Hypothalamic inhibitory factor for Prolactin
dopamine, PIF
very low ACTH levels suggest
adrenal source of corticol secretion
Test used for ACTH secreting adenomas
Dexamethasone suppression test
Cushings syndrome vs. disease
glucocorticoid excess v. ACTH secreting adenoma
Diabetes vs. SIADH symptoms
polyuria, polydipsia
lethargy, coma, seizures
Hormone probz diabetes vs. SIADH
deficiency of ADH (neurogenic) or insensitivity of kidneys to ADH (nephrogenic)
excess ADH
Diagnostic test diabetes vs. SIADH
low urine osmolality, increased plasma osmolality dose of subcuatenous vasopressine, positive if rise in urine osmolality
low sodium w/ elevated urine osmolality