Neurites Flashcards
Which organelles are present in dendritic shaft?
Mix of smooth/rough ER, Golgi complex, ribosomes,actin binding components
Which organelles are present in dendritic spine?
Smooth ER, mitochondria, Golgi
What is the canonical pathway of for transport of membrane proteins to the spine?
Membrane proteins arrive in transport vesicles (AMPAR)
What is the alternate pathway?
proteins are transported and modified in smooth ER and sent to Golgi outpost for regulated release
What is the spine apparatus?
Special form of ER that’s involved in local protein synthesis
What organelles are located in axon shaft?
No organelles except smooth ER
What organelles are located in axon terminals?
Smooth ER, ribosomes, mitochondria
How do neuropeptides reach the synaptic terminal?
through FAT within dense core vesicles
How are small molecule NT’s made in axon terminal?
Precursor molecules from SAT/uptake are modified by enzymes and endosomes to create final vesicle
Where do synaptic vesicles come from?
Local membrane biogensis
Are there Golgi complex in the synaptic terminal?
No
