Neural Conduction Flashcards

Be a bad motherfucker on that action potential tip

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1
Q

the diff between internal and external charge of a neuron

A

membrane potential

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2
Q

how to measure membrane potentia?

A

microelectrode

One tip inside and other in the extracelluar fluid

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3
Q

inside charge of neuron is

A

-70mV

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4
Q

Na+ is

A

Sodium

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5
Q

Potassium is

A

K+

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6
Q

At rest there is are more ___outside and more ___ inside

A

Na+

K+

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7
Q

what creates pressure for Na+ to enter a neuron?

A

the electrostatic pressure from the Resting Membrane Potential due opposite charges attracting

AND

random motion

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8
Q

What is the function of the sodium/potassium pump?

A

Maintains membrane potential

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9
Q

what is the ratio of action for the Sodium Potassium pump?

A

3 Na+ out

2 K+ In

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10
Q

input from another cells results in

A

Post-synaptic potentials

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11
Q

What are the two possible effects when NTs bind to Post-syn-receptors?

A

Depolarize (excitatory PSP)

Hyperpolarize (inhibitory PSP)

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12
Q

all post-syn-potentials are

A

graded potentials

Amplitudes are proportional to the signals that elicit them

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13
Q

what amplitude is the Threshold of Excitation?

A

about 65mV

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14
Q

Action potentials are

A

all or nothing

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15
Q

Explain Spatial summation of an EPSP or IPSP

A

two simultaneous EPSP or IPSP will produce a greater -one

simultaneous IPSP and EPSP will cancel each other out

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16
Q

Explain temporal summation of EPSP and IPSP

A

Rapid succession of IP or EP can add up to a bigger one

PSP’s can outlast and superimpose on the next one.

17
Q

Tremor at rest is a symptom of

A

Parkinson’s

18
Q

A neuron is rest is said to be

A

polarized

19
Q

What are the two factors that pressure Na+ ions to enter resting neurons?

A

random motion

electrostatic pressure

20
Q

at rest, neurons have more _____ outside than inside

A

Na+

21
Q

Rising phase of AP?

A

Na+ channels open and ions rush in

K+ channels open and K+ ions leave

Once MP is depolarized, the Na+ channels close

22
Q

Repolarization Phase of AP

A

K+ channels stay open and ions keep leaving until -70mV is achieved.

23
Q

Hyperpolarization Phase of AP

A

K+ channels stay open and the MP gets to -90mV

24
Q

how long is the refractory period of an AP and what can’t happen?

A

1-2ms

Absolute refractory
Can’t fire again

25
Q

Relative refractory?

A

a neuron can fire again, but stim needs to be higher than normal.

26
Q

Transmission in myelinated axons is

A

saltatory conduction

27
Q

neurons are about ___ apart

A

20 nanometers

28
Q

3 types of ion transporters

A

Pumps (in and out) (atp energy)

Co-transporters (use energy from diffusion)

Exchangers (energy from diffusion)

29
Q

most ion channels are of two types….

A

Voltage (open close due to changes in polarization)

Lingand (open due to binding of NT or Neuromodulator to receptor associated with the channel)

30
Q
A