Neural Circuitry Flashcards
1
Q
What receptors are in the D1 receptor family?
A
D1 and D5
2
Q
What receptors are in the D2 receptor family?
A
D2, D3, D4.
3
Q
Where is the D1 receptor mainly found?
A
Striatum and neocortex.
4
Q
Where is the D5 recptor mainly found?
A
Hippocampus and hypothalamus.
5
Q
What is the second messenger system used by the D1 receptor family?
A
Cyclic Amp, PIP Hydrolysis, Ca(+2) mobilization, PKC activation.
6
Q
What is the second messenger system used by the D2 receptor family?
A
Cyclic Amp, K(+) currents, voltage-gated Ca(+2) currents.
7
Q
Where is the D3 receptor found?
A
Olf. tubercle, n. accumbens, hypothalamus.
8
Q
Where is the D2 receptor found?
A
Striatum, SNpc, pituitary.
9
Q
Where is the D4 receptor found?
A
Frontal cortex, medulla, midbrain.
