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Pharmacology > Drugs: Part Three > Flashcards

Drugs: Part Three Flashcards

1
Q

What kind of drug is Alipogene Tiparvovec (Glybera)? What is it used for?

A

It is a gene-therapy cure. It is used for Lipoprotein lipase deficiency.

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2
Q

What is Epoetin Alpha (Procrit, Epogen)?

A

Recombinant erythropoietin.

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3
Q

What is Darbepoetin Alpha (Aranesp)?

A

Sequence-modified, highly glycosylated EPO with increased half-life.

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4
Q

What is Peginesatide (Omontys)?

A

A chemically modified peptide that mimics erythropoietin.

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5
Q

What is Methoxy Polyethylene glycol-epoetin beta (Micera, CERA)?

A

A conjugate of EPO to polyethylene glycol. Gives a 20-fold longer half-life. It continuously activates the erythropoietin recepter.

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6
Q

What is Vadadustat?

A

HIF prolyl-hydroxylase inhibitor. (Allows for greater HIF2 production, allowing for more erythropoeitin under normal conditions.)

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7
Q

What kind of drug is Finasteride?

A

It is a selective inhibitor of type 2 5a-reductase.

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8
Q

What kind of drug is Flutamide?

A

Androgen receptor antagonist.

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9
Q

What kind of drug is Enzalutamide?

A

Androgen receptor antagonist.

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10
Q

What kind of drug is Bicalutamide?

A

Androgen receptor antagonist.

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11
Q

What kind of drug is Abiraterone (Zytiga)?

A

A CYP17 inhibitor.

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12
Q

What is Enanthate?

A

Inject-able testosterone.

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13
Q

What is Cypionate?

A

Inject-able testosterone.

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14
Q

What kind of drug is Norgestrel?

A

Progestin-only contraceptive drug.

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15
Q

What kind of drug is Norethindrone?

A

Progestin-only contraceptive drug.

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16
Q

What kind of drug are Penicillins?

A

Beta-lactams.

17
Q

What kind of drug are Cephlasporins?

A

Beta-lactams.

18
Q

What kind of drug is Augmentin?

A

Amoxicillin/clavulanate potassium. It is a B-lactamase inhibitor and a B-lactam.

19
Q

What kind of drug is Ciprofloxacin?

A

A Quinolone/Fluoroquinolone.

20
Q

What kind of drug is Azithromycin (Zithromax)?

A

A Macrolides

21
Q

What kind of drug is Minocycline?

A

A Tetracycline.

22
Q

What kind of drug is 5-fluorouracil?

A

An Anti-metabolite (Cytotoxic agent).

23
Q

What kind of drug is Paclitaxel (Taxol)?

A

A Microtubule Poison or Mitotic inhibitor.

24
Q

What kind of drug is Doxorubicin?

A

A Genotoxic agent.

25
Q

What is Imatnib (Gleevec)?

A

Kinase inhibitor (-nib) of BCR-ABlL, KIT, PDGFRalpha.

26
Q

What is Trastuzumab (Herceptin)?

A

A Monoclonal Antibody. (-mab).

27
Q

What kind of drug is Tamoxifen (Nolvadex)?

A

It’s a Selective estrogen receptor modulator.

28
Q

What kind of drug is Bevacizumab (Avastin)?

A

A Monoclonal Antibody. (-mab).

29
Q

What kind of drug is Nivolumab (Opdivo)?

A

A Monoclonal Antibody. (-mab).

Pharmacology (20 decks)

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