nervous system: synaptic transmission Flashcards

1
Q

Junctions between 2 neurons are

A

postsynaptic and presynaptic

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2
Q

Site where an action potential in one neuron affects the production of an action potential in another neuron

A

Synapse

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3
Q

2 types of synaptic transmission

A

electrical synapses and chemical synapses

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4
Q

electrical synapses does what

A

pass electrical signals, are bidirectional and fast

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5
Q

chemical synapses does what

A

uses chemical messengers or neurotransmitters

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6
Q

electrical synapses gap junction allows

A

electrical current to flow between adjacent cells

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7
Q

where is electrical synapses found

A

cardiac, smooth muscle, and some neurons and glia

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8
Q

chemical synapses- presynaptic terminal

A

synaptic vesicles contain chemical messenger neurotransmitter (NT)

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9
Q

chemical synapses- synaptic cleft

A

space between presynaptic and postsynaptic cell, neurotransmitter diffusion

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10
Q

chemical synapses- postsynaptic membrane

A

neurotransmitter receptors

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11
Q

are chemical synapses mono or bi directional

A

monodirectional

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12
Q

how are EPSP created

A

Na channel permeability is increased-> graded depolarization –> neuronal membrane closer together—-> EPSP created

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13
Q

How is IPSP created

A

K or Cl permeability increased –> graded hyper polarization —-> neuronal membrane potential farther away from threshold —> IPSP

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14
Q

most common inhibitor

A

GABA

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15
Q

most common excitatory neurotransmitter

A

glutamate

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16
Q

gaseous neurotransmitter

A

nitric oxide

17
Q

Glutamate is removed via ____ with the help of ____

A

reuptake, glutatamate transporters

18
Q

glial cells that assist with neurotransmitter removal

A

astrocytes

19
Q

2 families of receptors

A

ionotropic and metabotropic

20
Q

ligand-gated ion channels that when a ligand binds to the receptor membrane channel will open

A

ionotropic receptor

21
Q

7-transmembrane GPCRs, binding of neurotransmitter initiates a second messenger to modulate channel on neural membrane

A

metatropic receptor

22
Q

example of inotropic receptor

A

ligand gated channels-nicotinic cholinergic

23
Q

example of metatropic channels

A

GPCRs- muscarinic-cholinergic receptor

24
Q

GABAa is what type of receptor and GABAb is what type

A

ionotropic and metatropic

25
Q

many antidepressants block what to cause what result

A

neurotransmitter reuptake to increase the neurotransmitter concentration in the synaptic cleft and increased stimulation of correspond post-synaptic receptors