Nervous System Flashcards
tissue that is formed by a network of many billion nerve cells, all assisted by many more supporting cells
nervous tissue
3 basic functions of the nervous system
- Sensory - to detect
- Integrative - to process/analyze
- Motor - to elicit an appropriate motor response
division of the nervous system that includes the brain and spinal cord
Central Nervous System
division of the nervous system that consists of all the nervous tissue outside CNS
Peripheral Nervous System
what do you call the environmental changes that neurons respond to by altering the ionic gradient that exists across their plasma membranes
stimuli
this ionic gradient is also called an electrical potential but cells that can rapidly change this potential are said to be excitable or irritable
what do you call the environmental changes that neurons respond to by altering the ionic gradient that exists across their plasma membranes
stimuli
this ionic gradient is also called an electrical potential but cells that can rapidly change this potential are said to be excitable or irritable
Neurons react promptly to stimuli with a reversal of the ionic gradient also called ____.
membrane depolarization
the neuron’s rxn to stimulus is propagated across its entire plasma membrane from the place that received the stimulus. the propagation is called?
action potential
may also be called depolarization wave or nerve impulse
the nervous system develops from what embryonic layer?
ectoderm
ectoderm = outermost of the 3 embryonic layers
With signals from the underlying axial structure, the notochord, ectoderm on the mid-dorsal side of the embryo thickens to form the epithelial ____?
neural plate
the sides of the neural plate fold upward and grow toward each other medially to form the what?
neural tube
Cells of this tube give rise to the entire CNS, including neurons and most glial cells
As the neural tube detaches from the now overlying ectoderm, many cells separate from it and produce a mass of mesenchymal cells called the ____?
neural crest
Cells from the neural crest give rise to the entire PNS
what do you call the functional unit in both the CNS and PNS?
neurons
are neurons capable of mitosis?
no
cells that are smaller than neurons but far more outnumbers them; they are also known as support cells
glial cells
they are 10 times more abundant than neurons in the mammalian brain
division of the PNS that transmits action potentials from the periphery to the CNS
Sensory (Afferent) division
Sensory division may be further classified into Somatic (consciously) or Visceral (unconsciously)
division of the PNS that transmits action potentials from the CNS towards the periphery
Motor (Efferent) division
Motor division may be further classified into Somatic (consciously) or Autonomic (unconsciously)
a division of the ANS that maintains normal body homeostasis
parasympathetic division
has its ganglia within or near effector organs
a division of the ANS that maintains the body’s responses during emergencies and excitement
fight-or-flight
sympathetic division
sympathetic division has its ganglia close to the CNS
a division of the ANS that is located in the wall of the digestive tract
can function without input from the CNS or other parts of the PNS
Enteric Nervous System (ENS)
what are the 3 main parts of a neuron?
- cell body
- dendrites
- axon
this part of the neuron contains the nucleus and the cell’s organelles; serves as the synthetic or trophic center for the entire neuron
cell body (perikaryon or soma)
part of the neuron that is classified as the numerous elongated processes extending from the perikaryon and specialized to receive stimuli from other neurons
dendrites
also known as little trees; receiving end of a neuron
dendrites receive information from other neurons or receptors and transmit it toward the cell body
a single long process ending at synapses specialized to generate and conduct nerve impulses to other cells (eg, nerve, muscle, and gland cells)
axon
type of neuron with one axon and two or more dendrites; most common
multipolar neurons
type of neuron with one dendrite and one axon; comprise the sensory neurons of the retina, olfactory epithelium, and the inner ear
bipolar neurons
type of neurons that have two extensions; one towards the periphery and one towards the CNS
most sensory neurons are part of this type
pseudounipolar
type of neurons that have many dendrites but no true axon; do not produce action potentials but regulate electrical changes of adjacent CNS neurons
Anaxonic neurons
type of neurons based on function wherein action potential is conveyed to the CNS; most are unipolar in structure
Sensory Neurons
sensory neurons are ____, they receive stimuli from receptors throughout the body.
afferent
type of neurons based on function that convey action potentials away from the CNS to the effector organs in the PNS thru cranial and spinal nerves; most are multipolar in structure
Motor Neurons
Motor neurons are ____, sending impulses to effector organs such
as muscle fibers and glands.
efferent
type of neurons based on function wherein it is mainly located within the CNS between the sensory and motor neurons
Interneurons
keyword: between
this is seen sa reflex arc
____ motor nerves are under
voluntary control and typically innervate skeletal muscle
Somatic
____ motor nerves control the involuntary or unconscious activities of glands, cardiac muscle, and most smooth muscle.
autonomic
part of the neuron that contains the nucleus and surrounding cytoplasm, exclusive of the cell processes
cell body (perikaryon)
.
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A typical neuron has an unusually large, ____ nucleus with a prominent nucleolus, indicating intense synthetic activity
euchromatic or heterochromatic
euchromatic
what do you call the regions of the perikarya that have concentrated RER and other polysomes that are basophilic?
Nissl bodies (chromatophilic substance)
Usually covered with many synapses, ____ are the principal signal reception and processing sites on neurons
dendrites
In the CNS most synapses on dendrites occur on ____, which are dynamic membrane protrusions along the small dendritic branches, visualized with silver staining
dendritic spines
Most neurons have only ____ axon, typically longer than its dendrites
how many axons?
one
The plasma membrane of the axon is often called the ____ and its contents are known as _____.
Axolemma; Axoplasm
Axons originate from a pyramid-shaped region of the perikaryon called the ____?
axon hillock
Axons of interneurons and some motor neurons also have major
branches called ____ that end at smaller branches with synapses influencing the activity of many other neurons.
collaterals
Each small axonal branch ends with a dilation called a terminal
____ that contacts another neuron or non-nerve cell at a synapse to initiate an impulse in that cell.
bouton
It is an electrochemical process initiated at the axon hillock when
other impulses received at the cell body or dendrites meet a
certain threshold.
action potential
____ are sites where nerve impulses are transmitted from one neuron to another, or from neurons and other effector cells
Synapses
Most synapses act by releasing ____, which are usually small molecules that bind specific receptor proteins to either open or close ion channels or initiate second-messenger cascades.
neurotransmitters
The ____ (terminal bouton)
contains mitochondria and numerous ____ from which neurotransmitter is released by exocytosis
presynaptic axon terminal; synaptic vesicles
The ____ contains receptors for the neurotransmitter, and ion channels or other mechanisms to initiate a new impulse
postsynaptic cell membrane
the space between the presynaptic and postsynaptic membranes
synaptic cleft
Organelles and macromolecules
synthesized in the cell body move by____ along axonal microtubules via ____ from the perikaryon to the synaptic terminals
anterogade transport; kinesin
____ in the opposite direction along microtubules via ____ carries certain other macromolecules, such as material taken up by endocytosis (including viruses and toxins), from the periphery to the cell body
Retrogade transport; dynein
The action potential is propagated along the axon as a wave of membrane depolarization produced by
voltage-gated ____ & ____ channels
Na+ & K+
Synapse that is usually associated with and transmit a
nerve impulse to another neuron’s cell body (or soma)? to a dendritic spine?
Axosomatic synapse; Axodendritic synapse