Nervous system Flashcards
explain the conduction of a nerve impulse along myelinated fibres
- depolarisation occurs
- saltatory conduction at nodes of Ranvier
- cell membrane becomes permeable to sodium ions
- needs to reach theshold (-55mV)
- sodium ions inter the cell
- membrane becomes positive to outside
- potassium ions diffuse out
- hyperpolarisation
- sodium-potassium pump acts: sodium out and potassium in
- membrane returns to polarised state
- action potential triggers depolarsiation in adjacent membrane regions
explain the transmission of a nerve impulse across a synapse
- When action potential reaches the axon terminals it triggers calcium gates, causing calcium to flood into the axon terminal
- The calcium binds with vesicles containing neurotransmitters and allows them to move to the cell membrane, releasing the neurotransmitter into the synaptic cleft
- These neurotransmitters diffuse across the synaptic cleft and attach to receptors on the membrane of the next neuron (dendrites/post-synaptic membrane)
- Results in the initiation of an action potential in the post-synaptic neuron (sodium gates open into the dendrites)
how do neurotransmitters go away after transmission across a synapse
Diffusion
Re-uptake (back into the axon terminal to be used again)
Broken down
how is the nervous system protected
bone
meninges
cerebrospinal fluid
explain how bone protects the nervous system
Cranium protects brain, vertebral column protects spinal cord
Protects from physical injury
explain how meninges protects the nervous system
Holds brain and spinal cord in place, carry blood vessels to the brain
Inner layer: dura mater
- tough and fibrous
- sticks closely to cranium/vertebral canal
- anchors CNS to bone
Middle layer: arachnoid mater
- loose mesh of fibres
- connects with inner layer
Outer layer: pia mater is delicate
- contains many blood vessels
- sticks closely to the surface of brain and spinal cord
explain how cerebrospinal fluid protects the nervous system
Supports brain, gives it a medium to float in
shock absorber - protects from mechanical injury
Occupies space between meningeal layers
Circulates through 4 cavities in the brain and centre of spinal cord
Clear watery fluid containing cells, glucose, proteins, urea and salts
Formed from blood, circulates through CNS and takes nutrients to neurons and removes wastes and eventually returns to capillaries
give examples of neurotransmitters
acetylcholine
adrenaline
dopamine
histamine
list other functions of the cerebrospinal fluid
Shock absorber, protects from mechanical injury
Delivers nutrients to cells of CNS
Removes wastes
Regulates concentration of H+ and CO2, which regulates breathing
Maintains fluid to bathe cells of the brain
Transport chemical messengers around CNS
what are the 2 parts to the cerebrum
cerebral cortex
basal ganglia
describe the structure of the cerebral cortex
outer surface of cerebrum, grey matter - 2-4mm thick
folded - rounded ridges called convolutions, shallow downfolds calls sulci, deep downfolds called fissures
longitudinal fissures separate cerebral cortex into 2 cerebral hemispheres
hemispheres have four lobes: frontal, parietal, temporal, occipital
joining the hemispheres at the base of the longitudinal fissure is the corpus callosum (area of white matter)
what is the function of the cerebral cortex
involved in thinking, reasoning, learning, memory, intelligence, sense and responsibility
3 basic functions:
sensory areas: interpret impulses
motor areas: control muscular movement
association areas: intellectual and emotional processing
explain the structure of the basal ganglia
grey matter below cerebral cortex
composed of tracts - bundles of nerve fibres
mostly unmyelinated axons
outside of CNS
what is the function(s) of the basal ganglia
regulates muscle tone
integrates complex muscles actions in complicated, learned ways (e.g. walking)
what is the function of the cerebellum
takes place below conscious
receives information from inner ear and stretch receptors in skeletal cells
controls posture, balance and fine coordination of voluntary muscles
damaged cerebellum - jerky, uncontrolled movement