Neoplasms Flashcards
A patient with ACS (acute coronary syndrome) is being treated with a heparin infusion. What diagnostic finding suggests to the nurse that the treatment is effective?
a.) The patient’s PT is within the reference range
b.) Arterial blood gas sampling is positive for the presence of factor VIII
c.) The patient’s platelet level is below 100,000/mm3
d.) The patient’s activated partial thromboplastin time (aPTT) is 1.5 to 2.5 times the control value
d.) The patient’s activated partial thromboplastin time (aPTT) is 1.5 to 2.5 times the control value
What medications potentially alter platelet function? (Select all that apply)
a.) Antihypertensives
b.) Penicillins
c.) Sulfa-containing medications
d.) Aspirin-based drugs
e.) NSAIDs
a.) Antihypertensives
b.) Penicillins
c.) Sulfa-containing medications
d.) Aspirin-based drugs
e.) NSAIDs
A patient with hemophilia A has been brought to the ED after being involved in a MVA resulting in the fracture of his femur & internal bleeding. Rapid assessment has identified the source of bleeding & that the patient is current stable (VSS). What should the nurse anticipate next?
a.) Position the patient prone to minimize bleeding
b.) Establish IV access for administration of Vitamin K
c.) Prepare for administration of factor VIII
d.) Administer normal saline IV to increase circulating volume
c.) Prepare for administration of factor VIII
The patient is receiving a continuosu IV infusion of heparin. Based on the most recent lab data:
* PT = 13.2 (control 12.1)
* INR = 1.3
* aPTT = 72 (control = 39)
Which action should the nurse implement?
a.) Continue to monitor the infusion
b.) Prepare to administer protamine sulfate
c.) Have the laboratory reconfirm the results
d.) Assess the patient for bleeding
a.) Continue to monitor the infusion
The patient diagnosed with Type 2 DM is scheduled for bowel resection in the morning. Which medication should the nurse question administering to the patient?
a.) Ticlopidine (Ticlid), a platelet aggregate inhibitor
b.) Ticarcillin (Timentin), an extended spectrum antibiotic
c.) Pioglitazone (Actos), a thiazolidinedione
d.) Bisacodyl (Ducolax), a cathartic laxative
a.) Ticlopidine (Ticlid), a platelet aggregate inhibitor
Any medication that will prolong bleeding, as a platelet aggregate inhibitor does, should not be administered to the patient at least 2-3 days before surgery
Acute Myeloid Leukemia (AML)
- What is it?
- It is the most common type of what?
- What is the treatment?
KNOW THIS (IN RED)!!!
- It is a defect in stem cells that differentiate into all myeloid cells (monocytes, granulocytes, erythrocytes, & platelets)
Most common type of non-lymphocytic leukemia
- Treatment = aggressive chemotherapy - induction therapy, BMT, or PBSCT
What is the treatment for acute myeloid leukemia (AML)?
KNOW THIS (IN RED)!!!
Aggressive Chemotherapy
- Induction therapy
- BMT or PBSCT
Signs & Symptoms of Acute Myeloid Leukemia
- Increased risk of infection (s/s of infection are more subtle)
- Bleeding
- Bone pain
- Mouth sores
What is acute myeloid leukemia?
Defect in the stem cells that differentiate into all myeloid cells (monocytes, granulocytes, erythrocytes, & platelets)
What is Chronic Myeloid Leukemia (CML) & what is the cause?
KNOW THIS (IN RED)!!!
Mutation in myeloid stem cells due to mutation in philadelphia chromosome
What is the life expectancy of patients with Chronic Myeloid Leukemia (CML)?
KNOW THIS (IN RED)!!!
3 - 5 years
What are manifestations / signs & symptoms of Chronic Myeloid Leukemia (CML)?
KNOW THIS (IN RED)!!!
May be asymptomatic initially
- Malaise
- Anorexia / Weight loss
- Confusion
- Shortness of breath caused by leukostasis
- Enlarged, tender spleen
- Enlarged liver
Chronic Myeloid Leukemia
1.) What is the cause of CML?
2.) What is the life expectancy of patients with CML?
KNOW THIS (IN RED)!!!
1.) Cause = inheritance of Philedalphia Chromosome
2.) Life Expectancy = 3-5 years
What is Acute Lymphocytic Leukemia (ALL)?
Uncontrolled proliferation of immature cells from lymphoid tissue
- issue in bone marrow leading to uncontrolled proliferation of immature cells (leukocytes are immature & don’t work correctly)
Manifestations / Signs & Symptoms of Acute Lymphocytic Leukemia (ALL)
KNOW THIS (IN RED)!!!
- Bone, liver, & spleen pain
- Meningeal involvement like headaches, nuchal rigidity, photophobia, seizures