Degenerative Neuro Disorders

Question 1

What is Parkinson’s Disease (PD)? What are signs & symptoms of PD?

KNOW THIS (IN RED)!!!

Answer 1

Degenerative neuro disorder due to the depletion of dopamine

S/S:
* resting tremor
* rigiditiy
* bradykinesia
* diminished postural stability

Question 2

What is Parkinson’s Disease (PD) & what is the cause?

KNOW THIS (IN RED)!!!

Answer 2

Degenerative neuro disorder caused by a depletion of dopamine

Question 3

Signs & Symptoms of Parkinson’s Disease

KNOW THIS (IN RED)!!!

Answer 3

• Resting tremor
• Rigidity
• Bradykinesia
• Diminished postural stability

Question 4

What medications are used in the medical management of Parkinson’s Disease?

KNOW THIS (IN RED)!!!

Answer 4

• Anticholinergics
• Symmetrel (amantadine)
• Dopaminergics (like Levadopa)

Question 5

Surgical Treatment / Interventions for Parkinson’s Disease

KNOW THIS (IN RED)!!!

Answer 5

• Thalamotomy & Pallidotomy (ablative procedure)
• Deep brain stimulation

Question 6

What is Huntington’s Disase?

KNOW THIS (IN RED)!!!

Answer 6

Hereditary disease (loss of cells in basal ganglia & cortex)

• NO cure yet

Question 7

What is Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig’s Disease?

• Is there a cure?
• What is the prognosis?
• Signs & Symptoms

KNOW THIS (IN RED)!!!

Answer 7

Degeneration of upper & lower motor neurons

• NO cure
• Terminal prognosis: 2-5 years
• S/S: progressive weakness, muscular atrophy, no sensory involvement

Question 8

What are the signs & symptoms of Amyotrophic Lateral Sclerosis (ALS)?

KNOW THIS (IN RED)!!!

Answer 8

• Progressive muscle weakness
• Muscular atrophy
• No sensory involvement

Question 9

Medical Management of Amyotrophic Lateral Sclerosis (ALS)

KNOW THIS (IN RED)!!!

Answer 9

• GOAL: slow / halt steps in cell death process
• Individual approach must be taken, including having discussion about advanced directives