NCD- Neurocognitve Disorders Flashcards
Was dementia redefined in the DSM 5 as an NCD?
Yes
What are some recognized NCDs?
Vascular
Frontotemporal
NCDLB (Lewy Bodies)
AD (Alzheimer’s)
What differentiates major and mild NCD?
Level of function
True or false
To be a major NCD, independence in ADLs is impaired
FALSE: IADL
True or false
In mild NCD may be capacity for independence in IADLs though the person may need more time, more effort, and compensatory strategies
True
What is Alzheimer’s disease (AD)?
A progressive dementia that causes cognitive, functional, and behavioral changes
Does the prevalence of AD approximately double every 5 years after the age of 65 in developed nations?
Yes
In the US, AD is the 6th leading cause of death for what age groups?
ALL age groups
True or false
AD isn’t the single major cause of institutionalization of aged people
FALSE: IS THE MAJOR CAUSE
What is the etiology of AD?
Poorly understood
Diagnosis made by exclusion (ruling out other disease processes abs considering PMH)
Diagnostic tools not completely accurate (ex MRI, PET)
Research in diagnostics not a priority due to lack of effective treatments
What is the neuropathology of AD?
Cortical atrophy
Widened sulci
Ventricular enlargement
Caused by Neurofibrillary tangles and beta-amyloid plaques
Beta amyloid plaques
Plaques collected outside and around neurons
Neurofibrillary tangles
Tau protein
Abundance of abnormal structure of beta amyloid plaques and neurofibrillary tangles
Neurotransmitter abnormalities
What does Neurofibrillary tangles and beta-amyloid plaques cause?
Shrink in brain structure
What are beta amyloid plaques caused by?
Defective breakdown of amyloid precursor protein
What does plaques collected outside and around the neurons cause?
Neuronal death
What does neurofibrillary tangles contaminate?
Tau protein