Nature of Disease [Iris Transes] Flashcards
An infectious disease transmissible (as from person to person) by direct contact with an affected individual or the Individual’s discharges or by indirect means (as by a vector).
Ex: Measles, Dengue, Typhoid
Communicable Diseases
- Does not result from an (acute) inflectional process
- Cause premature morbidity, dysfunction, and reduced quality of life.
- Usually develop and progress over long periods
Non-Communicable Diseases
slowly progressive in humans
Insidious
Every two seconds, a person dies prematurely from an ___________
NCD
________ of premature deaths occur in low- and middle-income countries
85%
_______ billion per year in economic losses due to NCDs.
$500
Every ___ invested in proven NCD interventions in low- and lower middle-income countries will generate at least ____ in increased economic development or reduced health care costs by 2030.
$1
$7
-Cardiovascular disease (Coronary heart disease, Stroke)
- Cancer
- Chronic lung diseases
- Diabetes
- Chronic neurologic disorders (Alzheimer’s, dementias)
- Arthritis/Musculoskeletal diseases
Non-Communicable Diseases
Characteristics of NCDs
- Complex etiology (causes)
- Multiple risk factors
- Long latency period
- Non-contagious origin (non-communicable)
- Prolonged course of illness
- Functional impairment or disability
- Incurability
- Insidious onset
An aspect of personal behavior or lifestyle, an environmental exposure, or a hereditary characteristic that is associated with an increase in the occurrence of a particular disease, injury, or other health condition.
Risk Factor
A risk factor that can be reduced or controlled by intervention, thereby reducing the probability of disease.
Modifiable Risk Factor
The WHO has prioritized the following four:
- Physical inactivity
- Tobacco use
- Alcohol use
- Unhealthy diets
A risk factor that cannot be reduced or controlled by intervention.
Ex. Age, Gender, Race, Family history (genetics)
Non-Modifiable Risk Factor
Leading Causes of Death
- Cardiovascular disease (Coronary heart disease, Stroke)
- Cancer
- Chronic respiratory diseases
- Diabetes
Group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both.
Increased blood glucose level
Diabetes Mellitus
Diabetes Mellitus can develop:
o Retinopathy
o Nephropathy
o Cardiovascular disease
o Amputation
o Tissue damage
- Characterized by inappropriate hyperglycemia primarily a result of pancreatic islet β-cell destruction and a tendency to ketoacidosis.
- Can develop at any age but first develops in children and young adults.
- Previously known as juvenile diabetes
- Deficient in insulin production by the pancreas. Produce little to no insulin;
- Dependent on insulin to maintain QOL.
Type I Diabetes Mellitus
is a form of type 1 diabetes that has no known etiology, is strongly inherited, and does not have β-cell autoimmunity. Individuals with this form of diabetes have episodic requirements for insulin.
Idiopathic type 1 diabetes
- Characterized by hyperglycemia as a result of an individual’s resistance to insulin with an insulin secretory defect.
- Most patients of this type are obese or have an increased percentage of body fat distribution in the abdominal region.
- This type of diabetes often goes undiagnosed for many years and is associated with a strong genetic predisposition, with patients at increased risk with an increase in age, obesity, and lack of physical exercise.
Type II Diabetes Mellitus