Natural products as sources of drugs

Question 1

Which drug was isolated from bark?

Answer 1

Quinine

Question 2

Which plant extract was morphine synthesised from?

Answer 2

Opium

Question 3

Which plant extract was taxol synthesised from?

Answer 3

Yew tree

Question 4

Willow tree was used to produce which drug?

Answer 4

Aspirin

Question 5

When competing for nutrients, why do fungi have an advantage over bacteria?

Answer 5

Because fungi are capable of producing anti-bacterial agents

Question 6

Secondary metabolites are essential in life processes such as growth and life maintenance. True or false?

Answer 6

False

Question 7

How are secondary metabolites classified?

Answer 7

Based on structure - which depends on the way in which they are built up

Question 8

Beta lactam antibiotics e.g. penicillin belong to which class of secondary metabolites?

Answer 8

Specialised amino acids and peptides

Question 9

Which two drugs are examples of aromatic and non-aromatic polyketides?

Answer 9

Aromatic - tetracycline

Non-aromatic - erythromycin

Question 10

What are terpenoids and steroids assembled from?

Answer 10

Isoprene units

Question 11

What is the terpenoid that is used in the treatment of ovarian and breast cancer?

Answer 11

Taxol

Question 12

Give two examples of alkaloids

Answer 12

Ephedrine

Papaverine