Name that Skin Lesion

Question 1

Answer 1

Excoriation

Scratch.

Breaks epidermis and leaves a linear red mark

Question 2

Answer 2

Lichenification

Thick/rough skin with prominent markings

Result of repeated rubbing

Question 3

Answer 3

Macules

Flat circumscribed area distinguished by coloration

5mm or less

Question 4

Answer 4

Patches

Patches are macules that are over 5mm across

Question 5

Answer 5

Papules

Elevated lesion less than 5mm

Greater than 5mm = Nodule

Question 6

Answer 6

Plaque

Elevated, Flat-Topped Lesion

Usually greater than 5 mm

Question 7

Answer 7

Pustule

Discrete, pus-filled RAISED lesion

Pus + Papule = Pustule

Question 8

Answer 8

Scale

Dry, Plate-Like

Result of keratinization defects

Question 9

Answer 9

Vesicle/Blister

Fluid-filled raised area

Less than 5mm

Greater than 5 = Bulla

Question 10

Answer 10

Acantholysis

Loss of intercellular adhesion of keratinocytes

Question 11

Answer 11

Acanthosis

Diffuse epidermal hyperplasia

Question 12

Answer 12

Dyskeratosis

Abnormal keratinization occurring prematurely in cells/groups of cells below stratum granulosum

Question 13

Answer 13

Hyperkeratosis

Hyperplasia of the stratum corneum

Question 14

Answer 14

Letiginous

Melanocytes proliferate in a line along the basal cell layer

Occurs reactively OR as part of a melanocytic neoplasm

Question 15

Answer 15

Papillomatosis

Hyperplasia and enlargement of dermal papillae

Question 16

Answer 16

Parakeratosis

Keratinization via retention of the nuclei in the stratum corneum

Normal in some mucosae (Buccal mucosa)

Question 17

Answer 17

Spongiosis

Edema of the epidermis

Question 18

Answer 18

Contact Dermatitis

Eczema limited to the site of insult

Question 19

Answer 19

Erythema Multiforme

Targetoid lesions shared only with Lyme Disease

But the disease has a WIDE range of lesions

Question 20

Answer 20

Erythema multiforme

Question 21

Answer 21

Psoriasis

Salmon colored plaque with silver-white scales

Question 22

Answer 22

Lichen Planus

Pruritic

Purple

Polygonal

Plantar

Papules

Plaques

Question 23

Answer 23

Lichen planus Wickam Striae

Question 24

Answer 24

Oral Lichen planus

Question 25

Answer 25

Lichen Simplex Chronicus

Roughening of skin with appearance of Lichen

Rubbing or scratching

“Prurigo Nodularis”

Question 26

Answer 26

Impetigo

Infection

S. aurea or S. pyogenes

Honey colored crust of dried serum

Question 27

Answer 27

Candidiasis

Thrush/Yeast Infection

Fungal

Question 28

Answer 28

Viral Verrucae

Variety of HPV subtypes

vulgaris = papular, anywhere on body

plana = flat, on palms and face

plantaris/palmaris = foot, seems like callus

candyloma acuminatum = genitalia

Question 29

Answer 29

Subcorneal bulla

Question 30

Answer 30

Subepidermal bulla

Question 31

Answer 31

Suprabasal bulla

Question 32

Answer 32

Pemphigus vulgaris IF

Uniform deposition of antibodies along cell bodies in a fishnet pattern

Question 33

Answer 33

Pemphigus foliaceus IF

Antibodies depositied in superficial layer of epidermis

Question 34

Answer 34

Oral Pemphigus Vulgaris

Question 35

Answer 35

Pemphigus foliaceus

Subcorneal blistering at stratum granulosum

Rare, and more benign than vulgaris

Smaller and less severe blisters

Question 36

Answer 36

Bullous Pemphigoid

Subepidermal non-acantholytic vesicles

Blister fluid is rich in Eosinophils

Question 37

Answer 37

Dermatitis Herpetiformis

Granular IgA antibodies to epidermal transglutaminase deposited in tips of dermal papillae

Linked to Celiac’s Disease

Question 38

Answer 38

Dermatitis Herpetiformis IF

Notice fluorescnece concentrated in tips of papillae