Myelodysplasia Flashcards
1
Q
define myelodysplasia ?
A
Disorder of hematopoietic stem cells characterised by chronic cytopaenia
• Is a precursor to leukaemia
2
Q
which kind of leukaemia can myelodysplasia often turn into?
A
can turn into AML
3
Q
what is a cause of myelodysplasia?
A
chemotherapy
4
Q
what are symptoms of myelodysplasia ?
A
• Symptoms of Bone Marrow Failure o Anaemia - Fatigue - Dyspnoea - Pallor - Soft systolic murmur o Thrombocytopenia - spontaneous bruising - bleeding gums - menorrhagia - purpura o Neutropoenia - frequent and severe infections
5
Q
what will the bloods show?
A
o FBC - pancytopaenia
6
Q
what is the gold standard investigation?
A
• Bone marrow aspire or biopsy
