Antiphospholipid syndrome Flashcards
1
Q
Define antiphospholipid syndrome
A
• Acquired disorder characterised by the presence of antiphospholipid antibodies causing CLOTS
2
Q
main features?
A
- recurrent miscarriages
- venous and arterial thromboses
- thrombocytopenia
3
Q
what is a big associated?
A
SLE
4
Q
epidemiology of antiphopholipid syndrome?
A
• More common in young females
5
Q
sign in antiphospholipid syndrome?
A
• Livedo reticularis – (net-like, mottled rash)
6
Q
what are the gold standard antibodies to test for?
A
o Lupus anticoagulant
o Anti-cardiolipin antibodies
7
Q
what will the bloods show?
A
o Paradoxical RISE IN APTT
o Low platelets
