Mycoplasmataceae Flashcards
General term for Family Mycoplasmataceae
Mycoplasma or Mollicutes
Why is Gram staining not performed in identification of Mycoplasma spp.?
Because they are cell wall deficient.
Which bacteria is the smallest living organism?
Mycoplasma
Which classification of antibiotics is Mycoplasma resistant to?
Cell wall inhibitors such as beta lactams (i.e. cephalosporin and penicillin)
All are slow growers except for?
a. M. pneumoniae
b. M. hominis
c. U. urealyticum
b. M. hominis
- exceptionally rapid grower
Two (2) important genera of Family Mycoplasmataceae
- Mycoplasma
- Ureaplasma
Three (3) significant species of Family Mycoplasmataceae
- M. pneumoniae
- M. hominis
- U. urealyticum
Oxygen requirement of Family Mycoplasmataceae
Facultative anaerobe
All are facultative anaerobe, except:
a. M. pneumoniae
b. M. hominis
c. U. urealyticum
a. M. pneumoniae
- Aerobic
Mycoplasma are highly fastidious.
a. True
b. False
a. True
- Needs complex media for growth
Mycoplasma are highly fastidious. In order to cultivate it, what must the culture media include for its growth?
Cholesterol and fatty acids.
- Formerly referred to as Pleuropneumoniae-like organism (PPLO)
- Eaton agent
M. pneumoniae
First mycoplasma to be isolated
M. pneumoniae
Causes Primary Atypical Pneumonia/Walking
pneumonia/Community acquired atypical pneumonia
M. pneumoniae
Causes Non-gonococcal urethritis (NGU)
M. hominis and U. urealyticum
Agent(s) of Primary Immunodeficiencies (PID)
M. hominis and U. urealyticum
The two genital mycoplasma
M. hominis and U. urealyticum
Mycoplasma spp. that is fastidious but grows on SBA and Chocolate agar
M. hominis
Stain for Mycoplasma
Acridine Orange
- but it is non-specific
Ideal culture media for M. pneumoniae and M. hominis
SPF Broth
Solid media to recover M. hominis and Ureaplasma spp.
A8 Agar
Previously called T-strain Mycoplasma
U. urealyticum
Tends to develop colonies that are difficult to see by the naked eye
Ureaplasma
Member of anaplasmataceae that infects WBCs and forms Mulberry-like bodies within phagosomes
Genus Erlichia
- initially rickettsia
The genus that multiply in phagosomes of host WBC
Erlichia
The genus that multiply in cytoplasm of endothelial cells
Rickettsia
This is previously known as Ehrlichia phagocytophilium
Anaplasma phagocytophilium
This causes Human Granulocytic Anaplasmosis by the vector Ixodes ticks
Anaplasma phagocytophilium
Vector of Anaplasma phagocytophilium
Ixodes ticks
Vector of Ehrlichia chaffeensis
Lone Star Ticks
This causes Human Monocytic Ehrlichiosis by the vector Lone star ticks
Ehrlichia chaffeensis
How are Human Monocytic Ehrlichiosis and Human Granulocytic Anaplasmosis acquired?
They are arthropod-borne and acquired through bites.
Initially a member of family Rickettsiaceae but since it is not arthropod borne, it is no longer part of this family
Coxiella burnetii
Modes of transmission of Coxiella burnetii
- Inhalation of dried birthing fluids of several animals
- Ingestions of unpasteurized milk
This causes Q fever
Coxiella burnetii
Other name for Q fever
Query fever