Chlamydia / Chlamydophila Flashcards
Two (2) species that are previously under Chlamydia but became Chlamydophila.
- Chlamydophila pneumoniae
- Chlamydophila psittacci
Chlamydia/Chlamydophila are sensitive to what type of drugs?
Sulfa drugs
Chlamydia/Chlamydophila are what type of organisms?
Obligate intracellular organisms
Two (2) distinct forms of Chlamydia/Chlamydophila
- Elementary body
- Reticulated body
A distinct form of Chlamydia that is Infectious, has spore-like features, extracellular, and metabolically inert.
Elementary body
A distinct form of Chlamydia that is non-infectious, replicative form, and intracellular.
Reticulated body
What is the prominent component of membrane found in the Elementary body that contributes to the resistance to environmental/physical stress?
Major Outer Membrane Protein (MOMP)
Two (2) shapes of Elementary body
- Round
- Pear-shaped
Chlamydia/Chlamydophila spp. that has/have ROUND elementary body
C. trachomatis
C. psittaci
Chlamydia/Chlamydophila spp. that has/have PEAR-SHAPED elementary body
C. pneumoniae
What are the disease C. trachomatis can cause?
- Trachoma
- Lymphogranuloma Venereum (LGV)
- Reiter’s syndrome (reactive arthritis)
Chronic eye infection and number 1 cause of preventable blindness
Trachoma or Trachoma Inclusion Conjunctivitis (TRIC)
Previously the gold standard in Chlamydia spp. before the advent of Molecular techniques and PCR.
Cell or Tissue Culture
What are the three (3) tissue/cell culture used in cultivation of Chlamydia spp.?
- McCoy Cells
- HeLa cells
- Buffalo Green Monkey
Chlamydia spp. are able to grow in bacterial medium.
a. True
b. False
b. False
In order to cultivate Chlamydia/Chlamydophila spp., cell culture (that is also used for viral culture) is required for their growth.