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RUSVM Bacteriology > Mycoplasma > Flashcards

Mycoplasma Flashcards

1
Q

Mycoplasma live where in the body?

A

Inhabit mucous membranes of respiratory and repro tract - obligate parasites
Hemotrophic sp-> RBC
Affinity to ciliated epithelium

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2
Q

What do mollicutes colonies look like when grown in vitro

A

Fried egg appearance

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3
Q

What are the characteristics of mycoplasma?

A

Smallest free living bacteria

No cell wall
-> not seen on gram stain
-> susceptible to drying
> not susceptible to penicillin

Small genome

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4
Q

Mycoplasma belong to the class_____________

A

Mollicutes ‘soft skin’

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5
Q

How is mycoplasma transmitted?

A

Close direct contact

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6
Q

What are the 3 important members of mycoplasma

A

Mycoplasma -pathogen and commenal
Ureplasam -pathogen and commensal
Acholeplasma -commensal

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7
Q

Mycoplasma leads to important predisposition of

A

Secondary bacterial infection

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8
Q

How do mycoplasma evade the immuno system

A

Antigenic mimicry by absorbing host cell antigens

Persist by antigenic variation

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9
Q

How do mycoplasma cause damage

A

Direct - peroxidation, complement/AB lysis

Indirect - superantigenic immunomoducation

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10
Q

How is mycoplasma isolated in the lab

A

Specialized culture
Serum rich media
Colonies are not visible to naked eye

PCR, MADI TOF for subculture

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11
Q

What mycoplasma can infect swine?

A

M. Hyopneumoniae
M. Hyorhinis
M. Hyosynoviae
M. Suis

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12
Q

Mycoplasma hyopneumoniae causes _________________ of swine

A

Enzootic pneumonia of swine

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13
Q

Swine

Chronic respiratory disease 
No productive count
Unthrifty 
Decreased weight gain 
High morbidity
A

M. Hyopneumniae

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14
Q

M. Hyopenuoniae has ____________ activity that produces hyperplasia BALT

A

Mitogenic activity

Aka cuffing pneumonia

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15
Q

How do you prevent M. Hyopneumoniae?

A

Control SPF herd
Biosecurty
Monitor at slaughter
Immunization

Secondary bacterial infection

  • > pasturella
  • > hemophilus
  • > actinobacillus
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16
Q

What are the mycoplasma of cattle

A

M mycoides subsp mycoides
M bovis
Ureaplasma diversum
M bovoculi

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17
Q

Mycoplasma mycoides sub mycoides causes what disease?

A

Contagious bovine pleuropneumonia

M mycoides subsp mycoides

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18
Q

T/F: mycoplasma mycoides subsp mycoides is reportable

A

T

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19
Q

What is the most virulent mycoplasma of cattle?

A

Mycoplasma mycoides subsp mycoides

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20
Q

Cattle

Respiratory distress, coughing, nasal discharge, lethargy

Necropsy -> marbled apprerance of lung due to edema of the interlobular septa and fibrinopurulent exudate on surface

A

Contagious bovine pleuropheumonia

21
Q

Mycoplasma bovis causes infection of?

A

Upper respiratory tract

Mastitis

22
Q

What disease is caused by mycoplasma bovis?

A

Bronchopneumonia

Bovine respiratory disease compels

23
Q

Cattle

Mastitis causing decreased milk production, thickened milk with watery/purulent secretions, swollen udder, and arthritis/swollen joints.

A

Mycoplasma bovis

24
Q

_________________ can be normal commensal organisms of the lower urogenital tracts of the cow

A

Ureplasma diversum

25
Q

Mycoplasma bovigenitalium is a commensal of where?

A

Bovigenitaliusm …

A solid guess would be bovine genitals

Seminal vesiculitis in bull
Granular uveitis, vaginitis, endometritis, and abortions in cows

26
Q

What mycoplasma are in goats

A

M. Capricolum subsp caprpneumoniae

M. Agalactiae and (m. Putrefaciens)

27
Q

M. Capricolum subsp capripnumoniae causes what disease?

A

Contagious caprine pleuropneumonia
Fatal

REPORTABLE

28
Q

What are the 4 avian mycoplasmas ?

A

M. Gallisepticum REPORTABLE
M. Synoviae REPORTABLE

M. Melegridis (mainly in turkey)
M. Iowae (mainly in turkey)

29
Q

In your chicken and turkey farm you see..

Coughing, nasal discharge, tracheal rales, sinusitis with production of thick mucous exudate, and decreased egg production

What is this

A

M. Gallisepticum

30
Q

M. Meleagridis and M. Iowae cause what in turkeys?

A

Respiratory disease, skeletal deformities, and decreased egg hatachability

31
Q

Chickens and turkeys with synovitis resulting in lameness, swelling of joints, and retarded growth

A

M. Synoviae

32
Q

Cats with mild respiratory infections and mycoides conjunctivitis. Who else can get this?

A

M. Felis

Horses -> selflimiting pleuritis

33
Q

Cats with arthritis and subcutaneous abscess

A

M. Gatae

34
Q

Dog urogenital tract disease in males and females

A

M. Canis

35
Q

Sheep with pneumonia secondary to other bacteria

A

M. Ovipneuomoniae

36
Q

Horse with lower airway disease causing pleural effusions. What is causing this? What secondary infection is the horse predisposed to?

A

M. Felis

Secondary - S. zooepidemicus

37
Q

How do you diagnose a mycoplasma infection?

A

Culture- > difficult requiring special media

Species specific serology

38
Q

How do you treat a mycoplasma infection

A

Antimicrobials

Macrolides
Tetracyclines
Linocosamide
Fluoroquinolones

39
Q

How do you control mycoplasma infection?

A

Test and cull
Biosecurity
Vaccination (limited– swine, CBPP, M.bovis, and poultry)
Control risk factors-> concurrent infections

40
Q

What is the principle target of mycoplasma hemofelis

A

RBC

41
Q

What disease is caused by mycoplasma hemofelis?

A

Feline infectious anemia

42
Q

Who is infected by mycoplasma hemofelis

A 
Simon Norman 
Minnie Mitten (these are the cats)

Not Bailey (butt) Winston (the dog)

43
Q

Cat

Fever, anemia, depression, weakness, icterus

A

Mycoplasma hemofelis

44
Q

Who is infected by mycoplasma hemosuis and what is the main target?

A

Swine

RBC

45
Q

Pig

Fever, anemia, weakness, icterus

A

Mycoplasma hemosuis

Outbreaks are associated with periods of stress

46
Q

Who is infected with M. Hemocanis

A

Doggo

47
Q

How do you diagnose a hemoplasma?

A

CBC, coombs test

Blood smear

PCR

48
Q

How do you treat a hemoplasma infection

A

Antimicrobials
Blood transfusion
Corticosteroids
IV glucose

49
Q

How do you control hemoplasma

A

Isolate and cull infected animals

Control invertebrate vectors (tick, flea, louse)

Test blood donors

RUSVM Bacteriology (7 decks)

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