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Innumology > Mycobacterium tuberculosis > Flashcards

Mycobacterium tuberculosis Flashcards

1
Q

Mycomembrane

A

Thick membrane containing lipid coat of mycolic acid (waxy)

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2
Q

TB immune evasion?

A

Inhibits phagosome maturation

  • inhibits Rab GTPase
  • down regulates proinflam cytokines (gamma interferon+receptor)
  • prevent antigen presentation of macrophage
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3
Q

TB has _________SS

A

T7SS

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4
Q

T7SS in TB uses ________in cytoplasm to facilitate substrate secretion

A

EspG +EccA

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5
Q

In T7SS of TB _______is the substrate

A

EsxA + EsxB

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6
Q

T7SS substrate processed ________

Found in __________(bacteria)

A

Periplasm

TB

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7
Q

T7SS needs _______ to operate

A

ATP

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8
Q

TB and _________ proliferate in ______

A

Yersina pestis

Macrophages

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Innumology (22 decks)

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