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ID Exam Four > Mycobacterial Agents > Flashcards

Mycobacterial Agents Flashcards

1
Q

First Line Agents

A

Isoniazid
Rifampin
Ethambutol
Pyrazinamide

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2
Q

Second Line Agents

A

PASA (P-AminoSalicyclic Acid)
Cycloserine
Ethionamide
FQ, Linezolid, Azithro, Interferon-gamma`

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3
Q

Isoniazid is active against?

A

TB

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4
Q

Isoniazid MOA

A

Blocks enzyme used to make the cell wall componenets

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5
Q

INH therapy should have?

A

B6 supplementation

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6
Q

INH ADR

A

Neuritis

Hepato

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7
Q

Rifampin as bling?

A

Resistance when used alone

Cidal against TB

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8
Q

Ethambutal used in

A

TB as a STATIC drug

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9
Q

Ethambutal MOA

A

Blocks cell wall synthesis via arabinosyl transferase

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10
Q

Ethambutal ADRs

A

EYEs

Decrease urate excretion –> gout attack

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11
Q

Pyrazidine MOA

A

Block fatty acyl synthase in mycolic acid synthesis

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12
Q

PASA MOA

A

Inhibit dihydropteroate synthase

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13
Q

Ethionamide requires?

A

B6 supplement

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ID Exam Four (11 decks)

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