myco Flashcards

1
Q

são

A

bacilos ácido-álcool resistentes

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2
Q

complexo tuberculose

A

M. tuberculosis, M. bovis, M. africanum

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3
Q

provoca doença em

A

10% infetados

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4
Q

clinica

A

TP em 80%
* única contagiosa
* tosse, hemoptises, febrícula, suores noturnos, perda de peso
extra-pulmonar

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5
Q

amostras

A

3 amostras respi por expetoração ou LBA, pelo menos 1 de manhã

  • homogeneizar com N-acetil-L-cisteína
  • descontaminação com hidróxido de sódio (método de Petroff)
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6
Q

gold standard diagnóstico

A

cultura

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7
Q

cultura pode ser

A
meios sólidos: 2-6 semanas
meios líquidos: 7 dias
* MGIT (O2)
* Lowenstein-Jensen
* Bactec... (CO2)
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8
Q

exame direto/baciloscopia

A

rápido
permite avaliar infecciosidade e resposta ao tratamento
falsos +

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9
Q

TAAN amostras

A

pulmonar
meningea
ganglionar
pericárdica

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10
Q

alternativa à baciloscopia

A

auramina-rodamina

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11
Q

diagnóstico TB latente

A

mantoux/tuberculina
IGRA

BCG e tal já se sabe

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12
Q

tratamento

A

2 meses isoniazida + rifampicina + pirazinamida + etambutol

4 meses só INH + RIF

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13
Q

resistências

A

MDR: INH e RIF

XDR: INH E RIF + qualquer injetável segunda linha (capreo, kana e amicacina)

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14
Q

pesquisa de resistência

A

com PCR para os genes

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15
Q

pesquisa de resistência quando

A

tratamento anterior
suspeita
contacto
profissionais de saude, HIV, toxico, reclusos, imigrantes…

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