Mutations Flashcards

1
Q

What is a mutation

A

A random change in the genetic material and nucleic acid of DNA or RNA.

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2
Q

What are point/substitution mutations

A

One base pair is swapped for another

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3
Q

What is a silent mutation

A

The change occurs in non-coding regions of DNA so it does not affect the phenotype

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4
Q

What is a missense mutation

A

The codon now codes for a different amino acid

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5
Q

What is a nonsense mutation

A

The change codes for a STOP codon, resulting in an incomplete protein

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6
Q

What is an insertion mutation

A

Extra base pairs are inserted into the DNA sequence

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7
Q

What is a deletion mutation

A

Base pairs are lost from the DNA

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8
Q

What is a duplication mutation

A

A section of the DNA is repeated

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9
Q

What is a translocation mutation

A

Sections of DNA either swap places or chromosomes join together

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10
Q

What is a beneficial mutation

A

A mutation that is beneficial to evolution

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11
Q

What is a neutral mutation

A

Has neither negative nor positive effects on the organism

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12
Q

What is a detrimental mutation

A

A mutation that is detrimental to the survival of the animal

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13
Q

What factors could cause a mutation?

A

External factors
Internal factors

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14
Q

Give examples of external factors that can cause a mutation

A
  • Chemicals
  • Radiation
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15
Q

Give examples of internal factors that can cause a mutation

A
  • A problem during DNA replication
  • Chromosomes and DNA strands can break
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16
Q

Explain a spontaneous mutation

A

They occur naturally. They are not frequent and are often unpredictable

17
Q

Explain an induced mutation

A

Alterations in the gene after it has come in contact with a mutagen and/or environmental causes

18
Q

Explain frameshift mutations

A

They can alter the point from where a codon (triplet of nucleotides) is read. It completely changes the amino acid sequence. This type of mutation may result in phenotypic changes