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Pharma final > MUST DO! > Flashcards

MUST DO! Flashcards

1
Q

Peripheral AD

A

Cilostazol- PDE3 inhib.
Vinpocetine
Nicergoline
Calcium dobesilate

ווין הוא פוץ אז יש לו פיאיידי

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2
Q

Acute migrane attack

A

Sumatriptan selective 5HT 1D/B

Ergotamine

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3
Q

Migrane prophylaxis

A 
Galcanezumab
Propranolol
Verapamil
Carbamazapine inhibit VGNC
Valproate
Imipramine
Cinnarizine
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4
Q

Positive iontropes

A

Digoxin
Milrinone is PDE inhib.
Levosimendan
Dobutamine

increase the strength of heart muscle contraction

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5
Q

Inhibitor of fatty oxidation in the cardiac myocites

A

Trimetazidine

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6
Q

Tolvaptan MOA

A

Orally active, specific V2 receptor antagonist

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7
Q

Histamine receptors

A

H1- Gq Allergy

H2-Gs Stomach

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8
Q

Why 1st gene antihistamine cause sedation?

A

They are lipophilic so cross BBB

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9
Q

1st gene antihistamines

A

Diphenhydramine

Promethazine- promise me

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10
Q

2nd gene antihistamines

A

Loratadine
Cetirizine
Dimetinden
Fexofenadin

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11
Q

Immunotherapy cytotoxic

A 
Cyclophosphamide
Azathiprine
Methotrexate
Leflonomide
Mycopholinic acid
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12
Q

Calcineurin is for

A

Activation of T cells

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13
Q

Sulfasalazine

A

PPAR gamma agonist
COX inhib.
For IBD

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14
Q

Rituximab

A

Anti CD20. Reduce B cell count
B cell lymphoma
Autoimmune
Solid organ transp.

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15
Q

Infliximab

Adalimumab

A

Anti TNFa

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16
Q

Natalizumab

A

Inhibts T cells

For MS. Chrons

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17
Q

Dupilumab

A

Anti IL4

Atopic dermatitis

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18
Q

6MP is for

A

CML
Acute leukemia
RA, IBD

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19
Q

Oxaliplatin is for

A

Colon cancer

20
Q

Bleomycin MOA, SE

A

Free radicals
Pulmonary fibrosis
Hyperpigmentation

For Hodgkins

21
Q

Dectinomycin is for

A

Wilms tumor

22
Q

Topo 1 inhib

A

Irinotecan for colon cancer

23
Q

Vincristine is for

A

Acute leukemia

24
Q

HER2

25
Q

BRAFi

MEKi

A

Dabratinib

Trametinib

26
Q

Aldesleukin

A

IL2 for renal cancer

27
Q

Progestins

A 
Medroxy-prog
Drospirone
Norethisterone
Levonogestrel
Desogestrel
28
Q

Anti progesterone

A

Mifepristone

Ulipristal acetate

29
Q

Contraceptive

A

Ethinylestradiol-Levonogestrel
Medroxyprogesteron
Levone, Dose

30
Q

Semisynthetic opiates

A 
Hydromorphone- analgestic
Oxycodone- analgestic
Dihydrocodeine- Antitussive
Buprenorphine- Withdrawl
Nalbuphibe- Spinal
Naloxone- acute toxic
31
Q

Synthetic opiates

A 
Fentanyl- analgestic
Tramadol- analgestic
Meperidine- analgestic
Loperamide
Diphenoxilate
Methadone
Naltrexone- withdrawl
32
Q

NSAIDs general

A

Aspirin
Colchicin
Alluporinol
Rasburicase

33
Q

NSAID’s that are not Aspirin

A 
Ibuprophen
Indomethacin
Naproxen
Diclofenac- MSK
Metamizole-SE agranulo
Katoprofen
Phenylbutazone- not safe
Meloxicam COX2
34
Q

Order of elim, Aspirin

A

Low- zero and than first

35
Q

Acute gaut

A

Naproxen

Cochicin- Microtubule

36
Q

Xanthine oxidase i

A

Alluporinol

Less purine metabolism

37
Q

Rasburicase

A

Uric acid into Allantoin

38
Q

Spasmolytics

A

Diazepam
Baclofen
Tizanidine
Tolperisone

39
Q

Ketolide

A

Telithromycin

40
Q

Streptogarmins

A

Quinopristine

Daflopristine

41
Q

Polymixin

42
Q

Fluroquinolone genes

A

2nd: Nor, Cipro, Ol
3: Levo
4: Moxi

43
Q

Glycopeptides

A

ze TOV
Teicoplanin
Oritavacin
Vancomycin

Bind D-ala-D-alaa

44
Q

Vanco SE

A

Red man synd

45
Q

Fosphomycin MOA

A

Inhibit NAG formation

Pharma final (24 decks)

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