Mushrooms Flashcards
What are the temporal and geographic locations of mushroom poisoning?
Most in north am. are not toxic, most exposures are in northeast.
When is mushroom toxicosis most common?
October (fall seasons)
What animals are affected by mushroom toxicity listed from most affected to least affected:
Canine> feline > porcine > avian
What does “Gyromitrin” toxicity present as?
GI signs followed by neuro signs, hepatorenal, +/- hemolytic syndrome
HEPATOTOXIC mushrooms effects (pathophys)?
Cyclopeptides interference with DNA synthesis leading to cellular necrosis
What is the pathophysiology of toxic mushrooms causing muscarinic issues?
Binding to muscarinic acetylcholine receptors in PNS and causes SLUD symptoms.
______ alters metabolism
Gyromitrin
Isoxazole effects of toxic mushrooms pathophysiology–>
Results in hyperesthesia (extreme sensation), sedation, and intermittent agitation
What medication should we NOT use if patient experienced isoxazole toxicity?
Benzos because can cause resp. depression/apnea due to potentiation of muscimol induced GABA effect
Prognosis is good with all mushroom toxicities besides ______ _____ has guarded to poor prognosis usually along with ____ and _____
Hepatotoxic mushrooms; gyromitrin; Nephrotoxicosis
Name the species with the class:
Hallucinogenic–> Psilocybe sp. Panaeolus sp
Hepatotoxic–> Amanita sp., Halerina sp., Lepitoa sp
Nephrotoxic–> Cortinarius sp.
Muscarinic–> Inocybe and Clitocybe sp. (SLUDDDD)
Gyromitrin–> Gyromitia sp., Helvella crispa, and H. lacunosa
Isoxazole–> Amanita gemmate, A Muscaria, A. smithiana, A. strobiliformis and Tricholoma muscarium
Hallucinogenic mushrooms pathophysiology –>
Stimulates serotonin and NE receptors in CNS and PNS, LSD like
things to help remember the different mushrooms……
Hallucinogenic= the ones that start with P (2) Hepatotoxic= Amanita, Halerina, Lepitoa Nephrotoxic= Cortinarius Muscarinic= "cybe" in the name (2) SLUDDDD Gyromitirin= Gyromitia sp., Helvella crispa/lacunosa Isoxazole = Amanita species and Tricholoma
