Musculoskeletal2 Flashcards

1
Q

Who does fibromyalgia usually ocur in

A

women (20-50yrs)

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2
Q

Risk factors for fibromyalgia

A

hypersensitive or prolonged stress response

history of prior trauma or osteoarthritis

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3
Q

What does a biopsy of tender areas in mm in fibromyalgia show

A

microstructural changes (ragged red fibers and mitochondrial changes)

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4
Q

What are mm fibers deficient in in fibromyalgia

A

ATP
phosphocreatine
serotonin

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5
Q

What is ATP

A

transports chemical energy for metabolism

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6
Q

what is phosphocreatine

A

provides rapid reserves of high energy

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7
Q

What is serotonin

A

influences mood, sexual desire/function, appetite, sleep, memory, learning, temp regulation, and social behavior

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8
Q

What are signs and symptoms of fibromyalgia

A
generalized mm aching
acute pain w/ palpitation of specific tender points
sleep disturbance
depression
anxiety
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9
Q

How to dx fibromyalgia

A

widespread pain for more than 3 months

11/18 tender points

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10
Q

where are tender points found

A

in the neck, shoulders, trunk and limbs (includes tendons and ligaments)

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11
Q

How to treat fibromyalgia

A
stress reduction
regular exercise
rest
local application of heat or massage PRN
antidepressants
nonesteroidal anti-inflammatory meds
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12
Q

What is the prognosis of fibromyalgia

A

little improvement

learn to manage the disorder to decrease symptoms

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13
Q

what can’t you use for meds in those with fibromyalgia

A

narcotic pain meds (may become adddicted)

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14
Q

What is RA

A

a chronic systemic disorder in which connective tissue throughout the body (joints) are damanged

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15
Q

What is RA probably due to

A

an autoimmune mechanism

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16
Q

When is peak onset of RA

A

middle adulthood (women 3:1)

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17
Q

What does RA do

A

attacks the synovium that lines the jts which destroys cartilage and bone w/in the jt.
Tendons and ligs which hold the bone together are weakened and stretched

18
Q

What is bone ankylosis

A

charateristic of RA

abnormal process of bones joining together w/ another bone causes complete immobility

19
Q

What kind of disorder is RA

A

Autoimmune disorder

20
Q

Signs and symptoms of RA

A
beings w/ vague systemic signs
fatigue
general aching
inflammation
stiffness
joint inflammation (one or several jts.)
21
Q

What is usually affected 1st in RA

A

hands and feet

22
Q

What are characteristic deformities of the hands

A

Swan neck
boutonniere
ulnar deviation

23
Q

What is swan neck deformity

A

hyperextended pip w/ flexion of DIP

24
Q

What is boutonniere deformity

A

hyperflexion of PIP and DIP hyperextension

25
What is tx for RA
``` balance b/t rest and activity OT Aspirin NSAIDS heat and cold splinting assistive devices adl training energy conservation surgery jt. protection ```
26
Wha can develop from RA
``` fatigue depression anorexia low grade fever affects adls and mobility ```
27
What is the prognosis of RA
more aggressive meds have resulted in preservation of function Long term outcome is poor
28
What is systemic lupus erythematosus (SLE) LUPUS
Chronic inflammatory disease that occurs when your body's immune system attacks your own tissues and organs
29
What is inflammation caused by Lupus affect
Different body systems: jts, skin, kidneys, blood cells, brain, heart, and lungs
30
Who does Lupus mostly occur in
women of childbearing years | african americans and hispanics
31
What is the etiology of Lupus
high levels of antinuclear antibodies in serum that targets normal tissue and signals the body to attack itself
32
Signs and symptoms of Lupus
vary greatly from person to person | nearly all organs potentially affected
33
What do you need to confirm the dx of Lupus
4 manifestations
34
What are the most common symptoms of Lupus
arthritis | butterfly rash
35
what is tx for lupus
prednisone (steroid) | avoid sun and excessive fatigue
36
What is the prognosis of lupus
improved but affects qol | fatalities becoming more rare
37
What are the manifestations of Lupus
``` Arthralgias/arthritis rupture of the intrapatellar and achilles tendon avascular necrosis of the femoral head skin manifestation (butterfly rash) renal damage pulmonary damage pericarditis myocarditis acute vasculitis ```
38
What is butterfly rash
red flat facial rash over bridge of nose and over cheeks
39
What is myocarditis
inflammation of heart muscle
40
wha is pericarditis
inflammation of pericardium surrounding heart
41
wha is acute vasculitis
impaired blood flow causing stroke or hemorrhages
42
What is fibromyalgia
syndrome of diffuse pain, specific tender points in mm, fatigue, sleep disturbance, depression and anxiety