Musculoskeletal2 Flashcards
Who does fibromyalgia usually ocur in
women (20-50yrs)
Risk factors for fibromyalgia
hypersensitive or prolonged stress response
history of prior trauma or osteoarthritis
What does a biopsy of tender areas in mm in fibromyalgia show
microstructural changes (ragged red fibers and mitochondrial changes)
What are mm fibers deficient in in fibromyalgia
ATP
phosphocreatine
serotonin
What is ATP
transports chemical energy for metabolism
what is phosphocreatine
provides rapid reserves of high energy
What is serotonin
influences mood, sexual desire/function, appetite, sleep, memory, learning, temp regulation, and social behavior
What are signs and symptoms of fibromyalgia
generalized mm aching acute pain w/ palpitation of specific tender points sleep disturbance depression anxiety
How to dx fibromyalgia
widespread pain for more than 3 months
11/18 tender points
where are tender points found
in the neck, shoulders, trunk and limbs (includes tendons and ligaments)
How to treat fibromyalgia
stress reduction regular exercise rest local application of heat or massage PRN antidepressants nonesteroidal anti-inflammatory meds
What is the prognosis of fibromyalgia
little improvement
learn to manage the disorder to decrease symptoms
what can’t you use for meds in those with fibromyalgia
narcotic pain meds (may become adddicted)
What is RA
a chronic systemic disorder in which connective tissue throughout the body (joints) are damanged
What is RA probably due to
an autoimmune mechanism
When is peak onset of RA
middle adulthood (women 3:1)