MUSCULOSKELETAL/NEURO Flashcards

1
Q

What is Creatinine Kinase an indicator of?

A

CK is an indicator of muscle breakdown
Causes of elevated CK:
-Rhabdomyolysis (causes AKI sec to myoglobin disposition)
-MI
-seizures
-severe infection
- prolonged shivering

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2
Q

S/S and Risk factors of idiopathic intracranial Hypertension

A

-Headache
-Visual changes and distubances

Risk factors:
-Female of childbearing age
-obesity
-Hypothyroidism
-Recent treatment of Doxycycline

MRI will come back with without any changes or abnormalities

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3
Q

What is increased ICP with no obvious cause treated with?

A

Analgesics such as Fentanyl are used to treat subclinical pain or agitation

ICP is treated when its over 20 mm Hg

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4
Q

What is the treatment for symptomatic cerebral salt washing?

A

A hypertonic saline solution of 3% sodium chloride because it rapidly increases serum sodium

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5
Q

What deficits will you see with a embolism of the anterior, middle and posterior cerebral artery

A

-Anterior ( voluntary movements - hemiplegia)
- Middle ( Aphasia)
- Posterior (sensory and visual loss)

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6
Q

What are the hallmark s/s of Normal Pressure Hydrocephalus ?

A
  • increase urinary incontinence
    -cognitive decline with disinhibition and aphasia
    -Gait disturbances with falls
    -ataxia
    -Restrictive eye movement with no enlargement of ventricles on imaging
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7
Q

S/S of Central Cord Syndrome?

A

Weakness more prominent in the upper extremities than the lower extremities

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8
Q

S/S of Horner Syndrome and diagnostic tool?

A

-Miosis
-Ptosis
-Anhidrosis
-MRA of the head and neck is most urgent to r/o Carotid artery dissection

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9
Q

Treatment for delirium not caused by ETOH or benzodiazepines withdrawal?

A

Dexmedetomidine Hydrochloride (Precedex) infusion

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10
Q

Management for patients with severe TBI with a GCS 3-8 and abnormal head CT

A

Intubation and ICP monitoring
High priority concern for TBI is cerebral edema (increased intracranial volume)

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11
Q

What test confirms Rhabdomyolosis and treatment?

A

CK level greater that 1000 U/L or at least 5x the upper limit of normal
- Prompt crystalloid resuscitation

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12
Q

Management of acute Subluxation of the acromioclavicular joint

A

-Sling to immobilize joint
-Ice to reduce swelling at the site
-NSAIDs to reduce inflammation and contribute to pain control

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13
Q

Why is Acute Respiratory Failure a complication of Guillian-Barre Syndrome?

A

-GB is a autoimmune attack of the peripheral myelin.
-Demyelintion of the nerves that innervate the diaphragm and intercostal muscles results in respiratory failure

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14
Q

Diagnostic standard to evaluate intracranial lesion

A

MRI with contrast/gadolinium

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15
Q

S/S of Brown-Sequard (hemicord) Syndrome

A

-Weakness, loss of vibration and proprioception ipsilateral to the site of injury
-Loss of pain and temperature on the opposite side

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16
Q

First-line agent for increased ICP

A

Mannitol 1gm/kg over 20 mins

17
Q

S/S of Giant Cell Arteritis

A

-Common in women who are 50 years and patient of Scandinavian descent
-Headaches
-Fevers
-Fatigue
- Muscle aches that started with stiffness and Pain in neck, shoulders, lower back, hips and thighs
-Elevated ESR and CRP

18
Q

S/S of Lewy Body Dementia

A
  • Fluctuating cognitive impairment
  • Rigidity
    -Bradykinesia
19
Q

S/S of Parkinson’s Disease

A
  • Resting Tremor
    -Rigidity
    -Bradykinesia
  • Hypomimia or mask-like face
  • Sleep disorders
    -Micrograhia
  • Microphonia
20
Q

S/S Myasthenia Gravis

A
  • Affect women in their early 20-30s and men in their 50-60s
  • Weakness later in the day or with repeated usage
  • facial and cranial weakness including eyelids, extraocular muscles with diplopia, ptosis and chewing and swallowing
    Symptoms improve after sleeping or rest
21
Q

Classic sign of Epidural Hematoma

A
  • Lucid interval between the head trauma and decline in consciousness
22
Q

Precursor of Guillian-Barre Syndrome and presentation

A

-Precursor: recent viral infections or immunization
Presentation:
- Neuropathic pain in the neck and back
-Ascending paralysis with loss of deep tendon reflexes
patient often require ventilator support including tracheostomy so measurement PF vital capacity is a priority.

23
Q

Cocaine s/s

A

-Seizures

24
Q

S/S of Cushing’s Triad

A

-Severe Hypertension
- Bradycardia
- Respiratory irregularity due to medullary dysfunction

25
Q

S/S of Multiple sclerosis

A

-Sensory loss
- Optic neuritis
-Weakness
-Paresthesia

26
Q

S/S of Physiologic Anisocira

A
  • One pupil slightly larger than the other
  • the size difference does not change in different lighting
27
Q

Treatment for non-displaced fractured coccyx

A

-Discharge home on Analgesics
-Bed rest for 3-4 weeks
-Follow up with orthopedics in 2-3 weeks of pain continues
Fracture generally heal on their own

28
Q

Treatment for type 2 amiodarone induced thyrotoxicosis

A

-Glucocorticosteroids

29
Q

Treatment for type 1 amiodarone induced thyrotoxicosis

A

Thionamide

30
Q

Rapidly progressing Cellulitis treatment

A

Penicillin
OR
Ceftriaxone
Clindamycin

31
Q

CAMRSA skin infections treatment

A

Bactrim
Doxycycline
Clindamycin

32
Q

Adverse effect of Nicardipine infusion

A

Reflex tachycardia
Add a Beta blocker (example Esmolol) to prevent