Musculoskeletal Good To Know Flashcards
What is osteoporosis
Osteoporosis is the loss of calcium in the bones in which the osteoclast activity outweighs the osteoblasts activity
When does bone stop absorbing calcium well
At age 30
Who are at risk of osteoporosis(7)
Menopause (lack of estrogen is bad because there's estrogen receptors on bones) Aging Steroids Lack of weight baring activities Lack of calcium intake Alcohol/cigarette use Some diseases
Osteoporosis puts you at risk of what
Fractures including the spine, wrist and hip (femoral neck)
Osteoporosis prevention includes
Yoga aerobics tai chi walking and resistance training
Osteoporosis is diagnosed by
Bone density test of hip and spine
DEXA (can direct 1% change in bone density)
What is the goal of drug therapy in osteoporosis
To prevent calcium loss and fractures and to rebuild bone
What is rheumatoid arthritis
And autoimmune inflammatory disease of the joints surrounding structures and other parts of the body
Local symptoms of rheumatoid arthritis are
Joint stiffness pain swelling and deformity
Systemic symptoms of rheumatoid arthritis are
Fever fatigue and weakness
What drugs treat rheumatoid arthritis
DMARD’s such as methotrexate and etanercept
How do DMARD’s treat osteoporosis
They decrease inflammation and damage by decreasing the immune response
What are two serious side effects of DMARD’s
Liver toxicity and bone marrow suppression
What pregnancy category are DMARDS
Pregnancy category ask because the drug interferes with DNA synthesis
What can a higher dose of methotrexate treat
Cancer
