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Pharm > MOA (neuro, msk, rsp) > Flashcards

MOA (neuro, msk, rsp) Flashcards

1
Q

Temazepam (Restoril)

BENZODIAZEPINE

A

Enhances GABA

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2
Q

Zolpidem (Ambien)

NONBENZODIAZEPINE

A

Enhances GABA

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3
Q

Baclofen (Lioresal)

CENTRALLY ACTING MUSCLE RELAXANTS

A

Enhances GABA

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4
Q

Phenytoin (Dilantin)

HYDANTOIN

A

Inhibits sodium influx through sodium channels

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5
Q

Carbamazepine (Tegretol)

IMINOSTILBENES

A

Inhibit sodium influx through sodium channels

Decreases the discharge of neurons

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6
Q 
Valproic acid (depakote)
VALPROIC ACID
A

Inhibits sodium and calcium and plug through sodium and calcium channels
Decreases neuron discharge
Enhances GABA

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7
Q

Antiepileptic drugs

A

Slows the entrance of sodium and calcium back into the neuron
Suppresses neuronal firing
Enhances GABA

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8
Q

Levodopa (Dopar)

DOPAMINE REPLACEMENT DRUGS

A

Crosses the blood brain barrier taken up by dopaminergic nerves and converted into dopamine

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9
Q

Donepezil (Aricept)

CHOLINESTERASE INHIBITOR

A

Prevents enzyme acetylcholinesterase from inactivating acetylcholine

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10
Q

Memantine (Namenda)

NMDA RECEPTOR ANTAGONIST

A

Blocks excess glutamate from NMDA receptor’s which decreases the influx of calcium into neurons in brain

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11
Q

Fluoxetine (Prozac)

SELECTIVE SEROTONIN REUPTAKE INHIBITORS

A

Selectively block reuptake of serotonin which strengthens serotonin transmission over time

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12
Q

Venlafaxine (Effexor)

SEROTONIN NOREPINEPHRINE REUPTAKE INHIBITORS

A

Block neuronal reuptake of serotonin and norepinephrine

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13
Q 
Bupropion hydrochloride (Wellbutrin) 
ATYPICAL ANTIDEPRESSANTS
A

Blocks dopamine reuptake in CNS

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14
Q

MAOI

A

Block MAO-A (inactivates serotonin and norepinephrine) and MAO-B (inactivated dopamine)
Increases amount of those neurotransmitters in synapse

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15
Q

Amitriptyline (Evail)

TRICYCLICS ANTIDEPRESSANTS

A

Block the reuptake of norepinephrine and serotonin

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16
Q

Raloxifene (Evista)

SELECTIVE ESTROGEN RECEPTOR MODULATOR

A

Activates estrogen receptors in endometrial tissue, which increases the risk of getting endometrial cancer, and in bones which DECREASES BONE RESORPTION. This blocks access to estrogen receptors in breast tissue which decreases the risk of estrogen dependent or receptor positive breast cancer.

17
Q

Alendronate (Fosamax)

A

Decreases bone resorption by decreasing the number and action of osteoclasts

18
Q

Calcitonin-salmon (Miacalcin)

CALCITONIN

A

Decreases bone resorption by inhibiting action of osteoclasts and increasing the excretion of calcium and decreasing serum calcium patients with hypercalcemia

19
Q

Calcium carbonate/citrate (Tums/Citracal)

CALCIUM SUPPLEMENTS

A

Provides a non-dietary source of calcium and neutralizes stomach acid

20
Q

Methotrexate and etanercept (Enbrel)

DMARDS

A

Immunosuppressive

Enbrel (DMARDS II) binds to tumor necrosis factor

21
Q

Albuterol (Proventil/Ventolin)

BETA2 ADRENERGIC ANTAGONIST

A

Simulate sympathetic nervous system by promoting bronchodilation which relieves bronchospasms

22
Q

Ipratropium (Atrovent)

INHALED ANTICHOLINERGIC

A

Blocks muscarinic receptors and bronchi which result in bronchodilation

23
Q

Theophylline (Theolair)

METHYLXANTHINES

A

Relaxin smooth muscle and bronchi and pulmonary blood vessels

24
Q

Beclomethosone/prednisone (QVAR)

GLUCOCORTICOID

A

Depresses information by preventing mediators like histamine from being released and preventing White blood cell action and this all decreases edema and airway

25
Q

Montelukast (singular)

LEUKOTRIENE MODIFIER

A

Suppresses inflammation by inhibiting release of leukotriene

26
Q

Diphenhydramine (Benadryl)

SEDATATIVE ANTIHISTAMINES

A

Binds to H1 receptors which blocks the release of histamine and is also a mild cholinergic blocker

27
Q

Cetirizine (Zyrtec)

NONSEDATING ANTIHISTAMINES

A

Bind to H one receptors blocking the action of histamine

Pharm (9 decks)

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