Ms. Pam's Pink Pig (cardiac, hemato) Flashcards
(45 cards)
Define depolarization in the heart
The inside of the cell goes from negative to positive. More Ca and Na goes in and K goes out.
Positive inotropic drugs
Epinephrine and calcium increase calcium availability which increases contractility and strengths the heart
Negative inotropic drugs
Beta blockers and calcium blockers that decrease calcium availability which decreases contractility which weakens heart
P wave
Atrial depolarization
QRS wave
Ventricular depolarization
T wave
Ventricular repolarization
Cardiac output calculation
Equals heart rate times stroke volume
Is the amount of blood exerted over one minute
Purposes of RAAS
Increases blood pressure
Define repolarization of the heart
Movement of ca and na out of cell and relaxes heart
Intracellular environment is more negative
Normal blood pressure
Below 120/80
Hypotensive blood pressure
Below 90/60
Hypertensive blood pressure
140/90 or greater
Prehypertensive blood pressure
130-139/80-89
Arterial pressure (AP)
Arterial pressure (AP) equals peripheral resistance (PR) times cardiac output (CO)
Cardiac Output (CO)
Cardiac output (CO) equals heart rate (HR) times stroke volume (SV)
losartan (Cozaar)
Angiotensin two receptor blocker (ARBs)
Treats: HTN, CVA, HF and migraines
What can’t you take the ACE inhibitor captopril (Capoten) with?
The ARB losartan or Cozaar
ARBs and ACE inhibitors can not be taken with each other but both of them can be taken with what drug
Thiazide diuretics
What is a major side effect of nifedipine (Procardia) and amlodipine (Norvasc) and what class to they belong to?
Calcium channel blockers with the major side effect of swelling of the peripheral (edema)
What do alpha 1 receptors do in peripheral and coronary blood vessels?
constriction
What do beta 2 receptors do in peripheral and coronary blood vessels?
dilation
Which receptor increases heart rate and force of contraction?
beta 1
Alpha 1 adrenergic blocker drug name and MOA
Name: doxazosin (Cardura)
MOA: blocks alpha 1 adrenergic receptors promoting vasodilation
Beta 1 adrenergic blocker drug name and MOA
Name: atenolol (Tenormin) or metoprolol (Lopressor)
MOA: selectively blocks beta 1 adrenergic receptors in the myocardium which results in a decrease in: cardiac output, peripheral resistance and myocardial oxygen consumption