Muscle Systems Flashcards
Skeletal muscles are ….?
multinucleate, striated, and covered by endomysium
Muscle fascicles are …?
bundles of muscle fibers which are covered by perimysium
The muscle trunk is …?
a bundle of fascicles and is covered by epimysium and fascia
The connective tissue of muscles is …?
bound firmly to the connective tissue of the tendon.
-which connects to the periosteum and the bone matrix
A muscle fiber is …?
a single cell consisting of sarcolemma, sarcoplasm, several nuclei, and myofibrils
Myofibrils are …?
bundles of thick and thin filaments which are covered by sarcoplasmic reticulum
What are organized into sarcomeres?
Thick and thin filaments
Thin filaments are composed of …?
actin, tropomyosin, and troponin
Thick filaments are composed of …?
myosin
Events of a Muscle Contraction
1st Action
The action potential in the motor neuron reaches the axon termini, which release acetylcholine [ACh].
Events of a Muscle Contraction
2nd Action
ACh diffuses across the cleft of the neuromuscular junction, inducing an action potential, which spreads over the sarcolemma and down the T tubules.
Events of a Muscle Contraction
3rd Action
The action potential reaches the sarcoplasmic reticulum, causing the SR to release Ca++.
Events of a Muscle Contraction
4th Action
Ca++ binds to troponin, troponin-tropomyosin moves, exposing myosin-binding sites on actin.
Events of a Muscle Contraction
5th Action
Myosin head attaches to actin [=crossbridge formation]; myosin head changes shape, thick and thin filaments slide past each other.
Events of a Muscle Contraction
6th Action
Z-discs are drawn toward each other; sarcomeres shorten; muscle fiber shortens; muscle shortens.