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BIOSCI107 II > Muscle [Comparing] > Flashcards

Muscle [Comparing] Flashcards

1
Q

T tubules

A

Yes except smooth muscle

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2
Q

SR

A

Skeletal extensive
Cardiac rudimentary
Smooth
Miniminal

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3
Q

Source of Ca2+

A

Skeletal: SR in response to Na+ influx.
Cardiac: interstitial fluid + SR via Ca2+ influx.
Smooth: Interstitial fluid + SR via IP3.

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4
Q

Regulatory proteins

A

Troponin/tropomyosin except calmodulin/MLCK for smooth muscle

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5
Q

Initiation of contraction

A

Skeletal: Neurogenic
Cardiac: Myogenic
Smooth: Neurogenic/Myogenic/Chemical

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6
Q

AP duration

A

Skeletal: 1ms
Cardiac: >100ms
Smooth: variable

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7
Q

Trigger for Ca2+ release (cardiac vs skeletal)

A

Skeletal: Na+ influx voltage gated
Cardiac: Ca2+ influx (CICR)

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8
Q

Effect of increasing calcium release for skeletal and cardiac

A

Skeletal: contraction all/none. Troponin always saturated.
Cardiac: contraction graded. Troponin usually saturated.

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9
Q

Conductivity skeletal vs cardiac

A

Electrically isolated vs electrically coupled

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BIOSCI107 II (18 decks)

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