Blood and Immune [Cell Immunity MHC]

Question 1

What are haemopoietic lymphoid precursors?

Answer 1

Another name for immature lymphocytes

Question 2

If lymphocytes respond to MHC class 1, what are they and what do they do?

Answer 2

CD8 cytotoxic T cells (CTL) that kill other infected cells.

Intracellular, viruses

Question 3

If lymphocytes respond to MHC class 2, what are they and what do they do?

Answer 3

CD4 helper cells that respond by secreting cytokines.

Extracellular, bacteria

Question 4

Process of T cell recognising MHC and binding:

Answer 4

TcR recognises that an antigen has inserted into the groove of the MHC molecule. The antigen binding surface of the TcR binds to top of MHC. T cell remains attached to membrane whole time.