Muscle

Question 1

Where is CK-MB found?

Answer 1

Heart

Question 2

Where is CK-MM found?

Answer 2

Muscle

Question 3

Where is CK-BB found?

Answer 3

Brain

Question 4

Why should you wait 30 min after a meal before swimming?

Answer 4

All blood in gut and skeletal muscle have ran out of ATP

Question 5

How does a neurogenic muscle disease present?

Answer 5

Distal weakness + fasciculations

Question 6

How does a myopathic muscle disease present?

Answer 6

Proximal weakness + pain

Question 7

What is a light chain composed of?

Answer 7

Actin

Question 8

What is a heavy chain composed of?

Answer 8

Myosin

Question 9

What band of the sarcomere does not change length?

Answer 9

A band

Question 10

Where are the T tubules located?

Answer 10

Cardiac muscle: Z line

Skeletal muscle: A-I junction

Question 11

Duchenne’s Muscular Dystrophy

Answer 11

Dystrophin frameshift, Gower sign, Cale pseudohypertrophy

Question 12

Becker’s Muscular Dystrophy

Answer 12

Dystrophin missense, symptoms > 5yo

Question 13

Myotonic Dystrophy

Answer 13

Birds beak face, can’t let go when shaking hands

Question 14

Myasthenic Syndrome = Lambert-Eaton

Answer 14

Gets stronger as day goes by, stronger with EMG, not small cell CA associated

Question 15

Myasthenia Gravis

Answer 15

Gets weaker as day goes by, stronger with Edrophonium, weaker with EMG, rule out thymoma

Question 16

Multiple Sclerosis

Answer 16

Anti-myelin antibody, young woman with vision problems, symptoms come and go

Question 17

Metachromatic Leukodystrophy

Answer 17

Arylsulfatase deficiency, kid with MS presentation

Question 18

Ataxia Telangectasia

Answer 18

Spider veins, IgA deficiency

Question 19

Freidrich’s Ataxia

Answer 19

Retinitis pigmentosa, scoliosis

Question 20

Adrenal Leukodystrophy

Answer 20

Carnitine shuttle problem, adrenal failure

Question 21

Guillane-Barre

Answer 21

Ascending paralysis, 2 weeks after URI

Question 22

ALS - Amyotrophic Lateral Sclerosis aka Lou Gehrig’s Disease

Answer 22

Middle age male with fasciculations, descending paralysis, no sensory problems

Question 23

Werdnig-Hoffman

Answer 23

Fasciculations in a newborn, no anterior horns

Question 24

Polio

Answer 24

Asymmetric fasciculations in child, 2 weeks after gastroenteritis

Question 25

Choreoathetosis

Answer 25

Dance-like movements, wringing of hands, quivering voice

Question 26

Atonic Cerebral Palsy

Answer 26

No muscle tone, floppy