Muscle Flashcards

0
Q

Motor unit definition

A

Somatic motor neuron together with all of the muscle fibers that it innervates

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1
Q

What surrounds muscle fibers

A

Sarcolemma

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2
Q

Muscle fibers going from big to small starting at muscle itself

A

Muscle to fascicle to fiber to myofibrils to filaments

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3
Q

Thin filaments

A

Actin

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4
Q

Thick filaments

A

Myosin

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5
Q

What makes up the Iband. what is in the middle of the Iband.

A

Myosin.

Z disc

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6
Q

What makes up the a band. What is in the middle of the A band. Why does the middle look the way it does

A

Thick filaments. h band. The H band is only myosin where as the rest of the a band has Actin also

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7
Q

Summarize excitation contraction coupling

A

release of ACH from nerve fiber, ACH binds to receptors on sarcolemma, opens ligand gated channels, Sodium defuses in producing depolarization, action potential produced. AP conducted a long transverse tubules, voltage gated CA channels open, CA released channels in SR open, CA diffuses into sarcoplasm, CA binds to troponin, stimulating contraction.

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8
Q

What is treppe

A

Ability to evoke stronger contractions after subsequent contractions. Staircase effect

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9
Q

Iso tonic contraction

A

Muscle is contracting during shortening. Iso means same tonic means strength

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10
Q

Isometric contraction

A

Contraction without muscle shortening. Holding a dumbbell with partially flexed arm

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11
Q

Concentric contraction

A

Iso tonic contraction where muscle shortens

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12
Q

Eccentric contraction

A

I so tonic contraction where muscle length and

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13
Q

What two things are different in cardiac muscle from skeletal muscle

A

Cardiac muscle does not require neural stimulation to contract – cardiac cells have own pacemaker. Action potentials are conducted from one of cardiac cell to another via intercalated disks

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14
Q

What six things are different between smooth and skeletal muscle

A

Not striated, no transverse tubules, calmodulin calcium binding instead of troponin, calcium enters from extracellular fluid and sarcoplasmic reticulum, nerve stimulation not required, gap junctions in most

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15
Q

Describe calcium reception and smooth muscle cells

A

Calcium binds to calmodulin which activates myosin light chain kinase. MLCK phosphoralyses myosin heads and allows for cross bridge attachment

16
Q

Single unit smooth muscle cells

A

Connected by gap junctions

17
Q

Multiunit smooth muscle cells

A

Not connected by gap junctions

18
Q

Synapses en passant

A

Autonomic neurons have varicosities that release neurotransmitters along the length of the smooth muscle cell

19
Q

Myosin head mechanism of function in skeletal muscle

A

ATPase enzyme splits ATP into ADP and phosphate activating crossed bridge. Phosphate is released to undergo a power stroke. ADP is then released and cross bridge is detached.

20
Q

H I and a bands – which shorten during contraction

A

H and I bands decrease a bands stay same length

21
Q

What surrounds the muscle

A

Epimysium

22
Q

What surrounds the fascicles

A

Perimysium

23
Q

What surrounds the muscle cells

A

Endomysium

24
Q

What does troponin I do

A

Inhibits crossbridge binding

25
Q

What does troponin T do

A

Binds to tropomyosin

26
Q

What does troponin C do

A

Binds to calcium

27
Q

Dihydropyridine and ryanodine receptors

A

Dihyrdro voltage gated ca receptors
Ryanodine ca release channels

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